A NOVEL STRATEGY FOR T CELL VACCINES
Grant number: 1084805 | Funding period: 2015 - 2017
Current vaccines rely on immune components in the blood. We are taking a different approach, which focuses on immunity at the body surfaces. These are the areas where pathogens first gain access to the body and we have shown that immune cells in these regions are far more potent than those that need to be recruited from the circulation.
Related publications (1)
Ptpn2 and KLRG1 regulate the generation and in skin
Katharina Hochheiser, Florian Wiede, Teagan Wagner, David Freestone, Matthias H Enders, Moshe Olshansky, Brendan Russ, Simone Nussing, Emma Bawden, Asolina Braun, Annabell Bachem, Elise Gressier, Robyn McConville, Simone L Park, Claerwen M Jones, Gayle M Davey, David E Gyorki, David Tscharke, Ian A Parish, Stephen Turner
Tissue-resident memory T cells (TRM cells) are key elements of tissue immunity. Here, we investigated the role of the regulator of..