REGULATION FROM THE OUTSIDE: CONTROL OF TRANSPORT AND ASSEMBLY OF MAJOR CELL WALL COMPONENTS IN MYCOBACTERIA

Grant number: 1064466 | Funding period: 2014 - 2016

Completed

Abstract

Tuberculosis (TB) kills nearly two million people each year while the causative bacterial species, Mycobacterium tuberculosis, infects one-third of the entire human population. An alarmingly high rate of TB exists in Australia's indigenous population. This proposal aims to identify and characterise essential processes that regulate synthesis of the outer coat of the bacterium, which are potential targets for new drugs for the treatment of this devastating disease.