UNDERSTANDING IMMUNITY TO INFLUENZA VIRUSES IN THE INDIGENOUS POPULATION

Grant number: 1091516 | Funding period: 2015 - 2024

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Abstract

Hospitalization rates and mortality from influenza are greatly increased in the Indigenous Australian population. As current vaccines are highly strain-specific, there is an urgent need for a one-shot universal vaccine that protects this vulnerable group against seasonal and pandemic influenza. Immunity provided by T cells is long-lasting, cross-protective and can prevent severe disease. Our findings will inform the design of effective T cell-based influenza vaccines for Indigenous populations.

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