Hiv Latency, Pathogenesis And Immunity

Grant number: 1052979 | Funding period: 2014 - 2018

Completed

Abstract

The development of cures, vaccines and better treatments for HIV/AIDS is an urgent global health priority. This team of seven groups in Sydney and Melbourne will study how HIV can lie dormant in some parts of the body, evading eradication by HIV therapy, as well as how the immune system responds to the virus. This will allow for design of novel vaccines and treatments. The researchers have skills in basic virology and immunology, and translating laboratory findings into human clinical trials.

Related publications (3)

HIV integration sites in latently infected cell lines: evidence of ongoing replication

Jori Symons, Abha Chopra, Eva Malantinkova, Ward De Spiegelaere, Shay Leary, Don Cooper, Chike O Abana, Ajantha Rhodes, Simin D Rezaei, Linos Vandekerckhove, Simon Mallal, Sharon R Lewin, Paul U Cameron

2017-01-13

Cancer therapies in HIV cure research

Thomas A Rasmussen, Jenny L Anderson, Fiona Wightman, Sharon R Lewin

2017-01-01

HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission

Mykola Pinkevych, Deborah Cromer, Martin Tolstrup, Andrew J Grimm, David A Cooper, Sharon R Lewin, Ole S Sogaard, Thomas A Rasmussen, Stephen J Kent, Anthony D Kelleher, Miles P Davenport

2015-07-01