AN AUTOMATED 3D ELECTRON MICROSCOPY FACILITY
Grant number: LE150100004 | Funding period: 2015 - 2016
The aim of this project is to establish the next generation of electron microscopy facility, with a fully automated tool enabling 3D imaging. The automated serial section system incorporated in a scanning electron microscope circumvents the limitation of transmission electron microscopy, which provides unique insights into molecular structures and cell components at high resolution, however, the area and volume are limited in size to a few microns. This new type of microscope can image whole organisms and be used by non-electron microscopists. It will be housed in an open access facility and will meet a growing demand for 3D electron microscopy.
Related publications (2)
An automated workflow for segmenting single adult cardiac cells from large-volume serial block-face scanning electron microscopy data
Akter Hussain, Shouryadipta Ghosh, Siavash Beikoghli Kalkhoran, Derek J Hausenloy, Eric Hanssen, Vijay Rajagopal
This paper presents a new algorithm to automatically segment the myofibrils, mitochondria and nuclei within single adult cardiac c..
An Automated Workflow for Segmenting Single Adult Cardiac Cells from Large-Volume Serial Block-Face Scanning Electron Microscopy Data
Akter Hussain, Shouryadipta Ghosh, Siavash Beikoghli Kalkhoran, Derek Hausenloy, Eric Hanssen, Vijay Rajagopal
<h4>ABSTRACT</h4> This paper presents a new algorithm to automatically segment the myofibrils, mitochondria and nuclei within sing..