Spinning Disk Confocal Microscope With Dual Stages

Grant number: LE150100011 | Funding period: 2015 - 2016

Completed

Abstract

Spinning disk confocal microscope with dual stages: This custom-built spinning disk confocal microscope with rotational stages will constitute an internationally unique platform. The system has the capability of rapidly monitoring cells in growing biological specimens under changing environments. It offers an integrated platform for multiple imaging strategies, including confocal and Total Internal Reflection Fluorescence (TIRF) microscopy. The system will reside in core facilities with open access to a broad research community. The system may be used to monitor a wide variety of cells and molecules, and will offer capabilities that are of importance to understand cell trafficking, disease a..

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Related publications (5)

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The sexual blood stages of the human malaria parasite Plasmodium falciparum undergo a remarkable transformation from a roughly sph..

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Role of plasmodium falciparum protein GEXP07 in Maurer’s Cleft morphology, Knob architecture, and P. Falciparum EMP1 trafficking

E McHugh, OMS Carmo, A Blanch, O Looker, B Liu, S Tiash, D Andrew, S Batinovic, AJY Low, HJ Cho, P McMillan, L Tilley, MWA Dixon

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The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) to..

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The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly

O Looker, AJ Blanch, B Liu, J Nunez-Iglesias, PJ McMillan, L Tilley, MWA Dixon

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Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood vessel walls by assembling a multi-protein com..

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Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development

M Parkyn Schneider, B Liu, P Glock, A Suttie, E McHugh, D Andrew, S Batinovic, N Williamson, E Hanssen, P McMillan, M Hliscs, L Tilley, MWA Dixon

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Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the hu..

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The elaborate route for UDP-Arabinose delivery into the Golgi of plants

C Rautengarten, D Birdseye, S Pattathil, HE McFarlane, S Saez-Aguayo, A Orellana, S Persson, MG Hahn, HV Scheller, B Ebert

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In plants, L-Arabinose (Ara) is a key component of cell wall polymers, glycoproteins, as well as flavonoids, and signaling peptide..