SPINNING DISK CONFOCAL MICROSCOPE WITH DUAL STAGES

Grant number: LE150100011 | Funding period: 2015 - 2016

Completed

Abstract

This custom-built spinning disk confocal microscope with rotational stages will constitute an internationally unique platform. The system has the capability of rapidly monitoring cells in growing biological specimens under changing environments. It offers an integrated platform for multiple imaging strategies, including confocal and Total Internal Reflection Fluorescence (TIRF) microscopy. The system will reside in core facilities with open access to a broad research community. The system may be used to monitor a wide variety of cells and molecules, and will offer capabilities that are of importance to understand cell trafficking, disease and signalling, plant biomass production, and climate..

View full description

Related publications (5)

Scholarly works icon

Plasmodium falciparum goes bananas for sex

Matthew WA Dixon, Leann Tilley

2021-07-01

The sexual blood stages of the human malaria parasite Plasmodium falciparum undergo a remarkable transformation from a roughly sph..

Scholarly works icon

Role of Plasmodium falciparum Protein GEXPO7 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking

Emma McHugh, Olivia MS Carmo, Adam Blanch, Oliver Looker, Boyin Liu, Snigdha Tiash, Dean Andrew, Steven Batinovic, Andy JY Low, Hyun-Jung Cho, Paul McMillan, Leann Tilley, Matthew WA Dixon

2020-03-01

The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) to..

Scholarly works icon

The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly

Oliver Looker, Adam J Blanch, Boyin Liu, Juan Nunez-Iglesias, Paul J McMillan, Leann Tilley, Matthew WA Dixon

2019-05-01

Plasmodium falciparum mediates adhesion of infected red blood cells (RBCs) to blood vessel walls by assembling a multi-protein com..

Scholarly works icon

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development

Molly Parkyn Schneider, Boyin Liu, Philipp Glock, Annika Suttie, Emma McHugh, Dean Andrew, Steven Batinovic, Nicholas Williamson, Eric Hanssen, Paul McMillan, Marion Hliscs, Leann Tilley, Matthew WA Dixon

2017-10-01

Transmission of malaria parasites relies on the formation of a specialized blood form called the gametocyte. Gametocytes of the hu..

Scholarly works icon

The elaborate route for UDP-arabinose delivery into the Golgi of plants

Carsten Rautengarten, Devon Birdseye, Sivakumar Pattathil, Heather E McFarlane, Susana Saez-Aguayo, Ariel Orellana, Staffan Persson, Michael G Hahn, Henrik V Scheller, Joshua L Heazlewood, Berit Ebert

2017-04-18

In plants, L-arabinose (Ara) is a key component of cell wall polymers, glycoproteins, as well as flavonoids, and signaling peptide..