Integrated Clinical and Scientific Studies in Post-Operative Crohn’s Disease

Abstract

Crohn’s disease is a chronic inflammatory bowel condition; the incidence in Australia is now amongst the highest in the world. Most patients require repeated invasive bowel surgeries when disease recurs. Using data from a past clinical trial comparing preventive treatments for recurrence; genetic, immunological and microbiological testing will be done on existing patient samples. This extensive data set will be analysed using systems biology methods to identify the cause of Crohn’s disease.