CENTRAL NEURAL REGULATION OF BROWN FAT FUNCTION – GLUCOSE SENSING AND CNS PATHWAYS
Grant number: 1082599 | Funding period: 2015 - 2018
Our research aims to identify how specific brain cells detect changes in glucose levels and how ageing and diet affect their function. We identified a subset of nerve cells that detect changes in glucose and the “hunger” hormone ghrelin, their ability to do so adapting with age and nutritional status. This project will investigate the potential of these nerve cells as targets for therapeutic and diet- intervention strategies to target obesity, diabetes and promote healthy ageing.