Prevention Of Multi-Drug Resistant Tuberculosis In A High Prevalence Setting: ‘Connecting The Dots’ In Vietnam

Grant number: 1081443 | Funding period: 2015 - 2019

Completed

Abstract

The close contacts of people with multi-drug resistant tuberculosis (MDR-TB) have a high risk of developing the disease. The V-QUIN MDR-TB Trial will evaluate the effectiveness of an oral antibiotic (levofloxacin) in preventing drug resistant TB among infected household contacts of TB patients. Household contacts from 10 Provinces in Vietnam will be randomly allocated to receive six-months of either levofloxacin or a placebo, and then followed for two years to see if they develop tuberculosis.

Researchers