Role of CCR6 and CXCR3 in Establishment and Maintenance of Latent HIV Infection

HIV integration sites and implications for maintenance of the reservoir

Jori Symons, Paul U Cameron, Sharon R Lewin

2018-03-01

PURPOSE OF REVIEW: To provide an overview of recent research of how HIV integration relates to productive and latent infection and..

HIV cure research: print and online media reporting in Australia

Jennifer Power, Bianca Fileborn, Gary W Dowsett, Jayne Lucke, Graham Brown, Jeanne Ellard, Sharon R Lewin, Joseph D Tucker, Sean Slavin, Jeremy Sugarman, Sophie Hill

2017-10-01

OBJECTIVES: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media inte..

Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals

Kersten K Koelsch, Thomas A Rasmussen, William J Hey-Nguyen, Chester Pearson, Yin Xu, Michelle Bailey, Katherine H Marks, Sarah C Sasson, Mark S Taylor, Robyn Tantau, Solange Obeid, Brad Milner, Orla Morrissey, Angie N Pinto, Kazuo Suzuki, Michael P Busch, Sheila M Keating, Philipp Kaiser, Steven Yukl, Joseph K Wong

2017-07-01

BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to significant changes to the HIV reservoir and HIV..

Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy

Gabriela Khoury, Remi Fromentin, Ajantha Solomon, Wendy Hartogensis, Marisela Killian, Rebecca Hoh, Ma Somsouk, Peter W Hunt, Valerie Girling, Elizabeth Sinclair, Peter Bacchetti, Jenny L Anderson, Frederick M Hecht, Steven G Deeks, Paul U Cameron, Nicolas Chomont, Sharon R Lewin

2017-03-15

Background: Immune activation and inflammation remain elevated in human immunodeficiency virus (HIV)-infected individuals receivin..

HIV integration sites in latently infected cell lines: evidence of ongoing replication

Jori Symons, Abha Chopra, Eva Malantinkova, Ward De Spiegelaere, Shay Leary, Don Cooper, Chike O Abana, Ajantha Rhodes, Simin D Rezaei, Linos Vandekerckhove, Simon Mallal, Sharon R Lewin, Paul U Cameron

2017-01-13

BACKGROUND: Assessing the location and frequency of HIV integration sites in latently infected cells can potentially inform our un..

Polymorphisms in the CD14 and TLR4 genes independently predict CD4( ) T-cell recovery in HIV-infected individuals on antiretroviral therapy

Yean K Yong, Esaki M Shankar, Ajantha Solomon, Tim Spelman, Christopher K Fairley, Julian H Elliott, Jennifer Hoy, Paul U Cameron, Adeeba Kamarulzaman, Sharon R Lewin

2016-09-10

BACKGROUND: Chronic HIV infection leads to marked depletion of CD4 T cells in the gastrointestinal tract and increased microbial t..