RESTORATION OF TUMOUR SUPPRESSION IN PROSTATE CANCER BY TARGETING THE UBIQUITIN PROTEASOME SYSTEM

E6AP promotes prostate cancer by reducing p27 expression

Dinesh Raghu, Piotr Jan Paul, Twishi Gulati, Siddhartha Deb, Christine Khoo, Andrea Russo, Enzo Gallo, Giovanni Blandino, Ai-Leen Chan, Elena Takano, Shahneen K Sandhu, Stephen B Fox, Scott Williams, Sue Haupt, Cristina Gamell, Ygal Haupt

2017-06-27

MDM4 is a rational target for treating breast cancers with mutant p53

Panimaya Jeffreena Miranda, Daniel Buckley, Dinesh Raghu, Jia-Min B Pang, Elena A Takano, Reshma Vijayakumaran, Amina FAS Teunisse, Atara Posner, Tahlia Procter, Marco J Herold, Cristina Gamell, Jean-Christophe Marine, Stephen B Fox, Aart Jochemsen, Sue Haupt, Ygal Haupt

2017-04-01

The role of MDM2 and MDM4 in breast cancer development and prevention

Sue Haupt, Reshma Vijayakumaran, Panimaya Jeffreena Miranda, Andrew Burgess, Elgene Lim, Ygal Haupt

2017-02-01

P53 at the start of the 21st century: lessons from elephants.

Sue Haupt, Ygal Haupt

2017-01-01

Crucial, natural protection against tumour onset in humans is orchestrated by the dynamic protein p53. The best-characterised func..

Uncovering a novel pathway for p16 silencing: Therapeutic implications for lung cancer

C Gamell, T Gulati, B Solomon, S Haupt, Y Haupt

2017-01-01

Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP

PJ Paul, D Raghu, A-L Chan, T Gulati, L Lambeth, E Takano, MJ Herold, J Hagekyriakou, RL Vessella, C Fedele, M Shackleton, ED Williams, S Fox, S Williams, S Haupt, C Gamell, Y Haupt

2016-12-01

Targeting Mdmx to treat breast cancers with wild-type p53

S Haupt, D Buckley, J-MB Pang, J Panimaya, PJ Paul, C Gamell, EA Takano, Y Ying Lee, S Hiddingh, T-M Rogers, AFAS Teunisse, MJ Herold, J-C Marine, SB Fox, A Jochemsen, Y Haupt

2015-07-01