Pre-Clinical Evaluation of a Novel Hiv-1 Vaccine Strategy
Grant number: 1093532 | Funding period: 2015 - 2016
Completed
Abstract
Recently, we have designed two mucosal HIV vaccine strategies that temporary block hormone-like molecules IL-4/IL-13 at the vaccination site inducing excellent antibody and killer T cell immunity with protective efficacy in small animals. This project aims to evaluate the safety and efficacy of these novel HIV mucosal vaccines prior to clinical evaluation.