GIVING AN ADULT LIFE AFTER FONTAN SURGERY TO THOSE WITH THE MOST SEVERE CONGENITAL HEART CONDITIONS

Impact of Fontan Fenestration on Long-Term Outcomes: A Propensity Score-Matched Analysis

Michael Daley, Edward Buratto, Gregory King, Leeanne Grigg, Ajay Iyengar, Nelson Alphonso, Andrew Bullock, David S Celermajer, Julian Ayer, Terry Robertson, Yves d'Udekem, Igor E Konstantinov

2022-06-07

Background The long-term impact of fenestration at the time of Fontan operation remains unclear. We aimed to review the early and ..

Fontan operation at less than 3 years of age is not a risk factor for long-term failure.

Jacob Y Cao, Supreet P Marathe, Diana Zannino, David S Celermajer, Robert N Justo, Nelson Alphonso, Yves d'Udekem, David S Winlaw

2022-02-18

OBJECTIVES: The age at which the Fontan operation is performed varies globally. Over the last decade, the median age of patients h..

Are we getting closer to identifying the best follow-up and management after Fontan completion?

Yves d'Udekem, Jean-Benoit Thambo, Ajay J Iyengar, Jack Rychik

2021-06-12

Path ahead for 'low risk' adolescents living with a Fontan circulation

David W Baker, Mark R Dennis, Diana Zannino, Chris Schilling, Patricia D Moreno, Andrew Bullock, Patrick Disney, Dorothy J Radford, Tim Hornung, Leeanne Grigg, Yves d'Udekem, Julian Ayer, David S Celermajer, Rachael Cordina

2021-04-01

OBJECTIVE: A high risk of morbidity and mortality is well documented in adults with a Fontan circulation. The difference in outcom..

Long-term outcomes following Fontan takedown in Australia and New Zealand

Supreet P Marathe, Ajay J Iyengar, Kim S Betts, Karin du Plessis, Gananjay G Salve, Robert N Justo, Prem Venugopal, David S Winlaw, Yves d'Udekem, Nelson Alphonso

2021-03-01

OBJECTIVE: Fontan takedown remains an option for the management of Fontan failure. We sought to evaluate early and late outcomes a..

Poor Late Outcomes After Tricuspid Valve Repair in a Single Ventricle: Experience of 103 Patients

Celest Dines Muntaner, Gregory King, Diana Zannino, Nelson Alphonso, Kirsten Finucance, David Winlaw, Christian Brizard, Robert Weintraub, Yves D'Udekem

2021-02-17

BACKGROUND: Outcomes of tricuspid valve repair in single-ventricle palliation are poor. We sought to identify the impact of repair..

Long-term Out-of-Hospital Health Care Use for Fontan Survivors Across Childhood

Li Huang, Kim M Dalziel, Karin du Plessis, David S Winlaw, Rachael Cordina, Andreas Pflaumer, Robert N Justo, Gavin R Wheaton, Andrew Bullock, Charlotte E Verrall, Yves D'Udekem

2020-10-01

BACKGROUND: Surgery is the cornerstone of treatment for single-ventricle patients, but life just begins for most when the staged p..

Heterotaxy Adverse Long-Term Outcomes After Fontan Completion

Supreet P Marathe, Diana Zannino, Jacob Y Cao, Karin du Plessis, Shilpa S Marathe, Julian Ayer, David S Celermajer, Thomas L Gentles, Gary F Sholler, Robert N Justo, Nelson Alphonso, Yves d'Udekem, David S Winlaw

2020-08-01

BACKGROUND: Heterotaxy is considered a risk factor for poor outcomes after the Fontan operation. However, long-term data to suppor..

Atrioventricular valve closure in Fontan palliation

Gregory King, David S Winlaw, Nelson Alphonso, David Andrews, Kirsten Finucance, Igor E Konstantinov, Yves D'Udekem

2020-05-01

OBJECTIVES: Atrioventricular valve regurgitation is known to adversely impact outcomes of single-ventricle palliation, and valve r..

Reintervention and survival in 1428 patients in the Australian and New Zealand Fontan Registry

Michael Daley, Karin du Plessis, Dianna Zannino, Tim Hornung, Patrick Disney, Rachael Cordina, Leeanne Grigg, Dorothy J Radford, Andrew Bullock, Yves d'Udekem

2020-05-01

OBJECTIVE: Patients undergoing single-ventricle palliation have experienced significant improvement in survival in the recent era...

Body Composition in Young Adults Living With a Fontan Circulation: The Myopenic Profile

Derek Tran, Paolo D'Ambrosio, Charlotte E Verrall, Chantal Attard, Julie Briody, Mario D'Souza, Maria Fiatarone Singh, Julian Ayer, Yves d'Udekem, Stephen Twigg, Glen M Davis, David S Celermajer, Rachael Cordina

2020-04-21

Background We sought to characterize body composition abnormalities in young patients living with a Fontan circulation and explore..

Does pregnancy impact subsequent health outcomes in the maternal Fontan circulation?

Emily Moroney, Diana Zannino, Rachael Cordina, Thomas Gentles, Yves d'Udekem, Dominica Zentner

2020-02-15

BACKGROUND: Pregnancy in women with a Fontan circulation is understood to have a significantly increased risk of maternal morbidit..

The Neurodevelopmental Outcomes of Patients With Single Ventricles Across the Lifespan

Karin du Plessis, Yves d'Udekem

2019-11-01

BACKGROUND: Moderate to severe neurodevelopmental impairments are recognized as a significant comorbidity in one-fourth to one-thi..

The impact of morphological characteristics on late outcomes in patients born with hypoplastic left heart syndrome

David P Newland, Chin L Poh, Diana Zannino, Patrick Elias, Christian P Brizard, Kirsten Finucane, David S Winlaw, Yves d'Udekem

2019-09-01

OBJECTIVES: Patients with hypoplastic left heart syndrome are at high risk of late adverse events after Fontan completion, but it ..

Prevalence and risk factors for low bone density in adults with a Fontan circulation

Paolo D'Ambrosio, Derek Tran, Charlotte E Verrall, Chantal Attard, Maria Fiatarone Singh, Julian Ayer, Yves d'Udekem, Stephen Twigg, David S Celermajer, Rachael Cordina

2019-08-20

OBJECTIVE AND PATIENTS: This study aimed to characterize bone mineral density abnormalities and pathophysiological associations in..

Augmentation of the pulmonary arteries at or prior to the Fontan procedure is not associated with worse long-term outcomes: a propensity-matched analysis from the Australia-New Zealand Fontan Registry

Lauren Shearer, Robert N Justo, Supreet P Marathe, Kim Betts, Prem Venugopal, David S Winlaw, Andrew Bullock, Terry Robertson, Thomas L Gentles, David Celermajer, Yves d'Udekem, Nelson Alphonso

2019-05-01

OBJECTIVES: Long-term data on the impact of pulmonary artery (PA) augmentation in patients who underwent the Fontan procedure are ..

Pacemakers are associated with a higher risk of late death and transplantation in the Fontan population

Chin L Poh, David S Celermajer, Leeanne E Grigg, Jonathan M Kalman, Mark A McGuire, Thomas L Gentles, Dorothy J Radford, Andrew Bullock, Patrick JS Disney, David Winlaw, Karin du Plessis, Yves d'Udekem

2019-05-01

BACKGROUND: The need for permanent pacing has been identified as a predictor of poor outcomes in the late survivors of Fontan surg..

Two Ventricles Are Not Better Than One in the Fontan Circulation: Equivalent Late Outcomes

Supreet P Marathe, Diana Zannino, William Y Shi, Karin du Plessis, Jascha Kehr, Gopinath Perumal, Jessica Sun, Thomas L Gentles, Julian Ayer, Gary F Sholler, Charlotte E Verrall, Nelson Alphonso, David Andrews, Yves d'Udekem, David S Winlaw

2019-03-01

BACKGROUND: A subset of patients who underwent Fontan operations has two adequate-sized ventricles, but an anatomic biventricular ..

Atrioventricular Valve Failure in Fontan Palliation

Gregory King, Julian Ayer, David Celermajer, Dominica Zentner, Robert Justo, Patrick Disney, Diana Zannino, Yves d'Udekem

2019-02-26

BACKGROUND: Atrioventricular valve failure (moderate or greater regurgitation, or valve operation) is a risk factor for adverse ou..

The Japanese cohort of adults with a Fontan circulation points to the action plan necessary to improve survival after Fontan

Yves d'Udekem, Chin L Poh

2019-02-01

Traversing the liminal: what can Fontan adults' transition experiences and perspectives teach us about optimizing healthcare?

Karin du Plessis, Rebecca Peters, Evelyn Culnane, Yves d'Udekem

2018-09-26

BACKGROUND: Successfully transitioning to adult care is important for congenital heart disease (CHD) patients, particularly those ..

Ask not what your Fontan can do for you, ask what you can do for your Fontan!

Yves d'Udekem, Nimani Fernando, Karin du Plessis

2018-07-01

"How long will I continue to be normal?" Adults with a Fontan circulation's greatest concerns

Karin du Plessis, Rebecca Peters, Ingrid King, Kirsty Robertson, Jonathan Mackley, Rachel Maree, Tracy Stanley, Louise Pickford, Brian Rose, Matthew Orchard, Helen Stewart, Yves d'Udekem

2018-06-01

BACKGROUND: Little is known about adults living with a Fontan circulation's concerns outside the scope of their clinical outcomes...

Long-term outcomes of single-ventricle palliation for pulmonary atresia with intact ventricular septum: Fontan survivors remain at risk of late myocardial ischaemia and death

Patrick Elias, Chin Leng Poh, Karin du Plessis, Diana Zannino, Kathryn Rice, Dorothy J Radford, Andrew Bullock, Gavin R Wheaton, David S Celermajer, Yves d'Udekem

2018-06-01

OBJECTIVES: The specific outcomes of patients with pulmonary atresia with intact ventricular septum late after Fontan palliation a..

Involvement of patients and parents in research undertaken by the Australian and New Zealand Fontan Registry

Yves d'Udekem, Victoria Forsdick, Karin du Plessis

2018-04-01

Research that is closely connected with the population it is studying and in which the translational value to healthcare is high i..

"Will she live a long happy life?" Parents' concerns for their children with Fontan circulation

Karin du Plessis, Rebecca Peters, Ingrid King, Kirsty Robertson, Jonathan Mackley, Rachel Maree, Tracy Stanley, Louise Pickford, Brian Rose, Matthew Orchard, Helen Stewart, Yves d'Udekem

2018-03-01

BACKGROUND: Families of children at the worst end of the congenital heart disease endure a significant burden which is often not c..

Hospital costs and cost implications of co-morbid conditions for patients with single ventricle in the period through to Fontan completion

Li Huang, Kim M Dalziel, Chris Schilling, David S Celermajer, John J McNeil, David Winlaw, Tom Gentles, Dorothy J Radford, Michael Cheung, Andrew Bullock, Gavin R Wheaton, Robert N Justo, Lisa A Selbie, Victoria Forsdick, Karin Du Plessis, Yves d'Udekem

2017-08-01

BACKGROUND: Patients undergoing palliative surgeries for single-ventricle conditions are affected by multiple comorbidities or non..

Hospital Inpatient Costs for Single Ventricle Patients Surviving the Fontan Procedure

Li Huang, Chris Schilling, Kim M Dalziel, Siyu Xie, David S Celermajer, John J McNeil, David Winlaw, Tim S Hornung, Dorothy J Radford, Leeanne E Grigg, Andrew Bullock, Gavin R Wheaton, Robert N Justo, Jayne Blake, Rachel Bishop, Karin Du Plessis, Yves d'Udekem

2017-08-01

We estimated the inpatient resource use for a Fontan patient from birth to adulthood and explored factors that might induce cost d..

The Cost Differential Between Warfarin Versus Aspirin Treatment After a Fontan Procedure

Chris Schilling, Kim Dalziel, Ajay J Iyengar, Yves d'Udekem

2017-08-01

BACKGROUND: The use of aspirin versus warfarin for treatment of patients after a Fontan procedure remains contentious. Current pre..

Improved long-term outcomes in double-inlet left ventricle and tricuspid atresia with transposed great arteries: systemic outflow tract obstruction present at birth defines long-term outcome

Lotte C Franken, Manouk Admiraal, Charlotte E Verrall, Diana Zannino, Julian G Ayer, Ajay J Iyengar, Andrew D Cole, Gary F Sholler, Yves D'Udekem, David S Winlaw

2017-06-01

OBJECTIVES: In 2 subtypes of functional single ventricle, double inlet left ventricle (DILV) and tricuspid atresia with transposed..

The Long-Term Management of Children and Adults with a Fontan Circulation: A Systematic Review and Survey of Current Practice in Australia and New Zealand

Ganesh K Gnanappa, David S Celermajer, Gary F Sholler, Tom Gentles, David Winlaw, Yves d'Udekem, Julian Ayer

2017-01-01

Although long-term survival is now the norm, Fontan patients face significant morbidity and premature mortality. Wide variation ex..

The Fontan epidemic: Population projections from the Australia and New Zealand Fontan Registry

Chris Schilling, Kim Dalziel, Russell Nunn, Karin Du Plessis, William Y Shi, David Celermajer, David Winlawf, Robert G Weintraub, Leanne E Grigg, Dorothy J Radford, Andrew Bullock, Thomas L Gentles, Gavin R Wheaton, Tim Hornung, Robert N Justo, Yves d'Udekem

2016-09-15

BACKGROUND: The number and age demographic of the future Fontan population is unknown. METHODS: Population projections were calcul..

Heart transplantation in Fontan patients across Australia and New Zealand

William Y Shi, Matthew S Yong, David C McGiffin, Pankaj Jain, Peter N Ruygrok, Silvana F Marasco, Kirsten Finucane, Anne Keogh, Yves d'Udekem, Robert G Weintraub, Igor E Konstantinov

2016-07-01

OBJECTIVE: Patients with Fontan physiology may eventually require heart transplantation (HT). We determined the rates and outcomes..

Use of ACE inhibitors in Fontan: Rational or irrational?

Thomas G Wilson, Ajay J Iyengar, David S Winlaw, Robert G Weintraub, Gavin R Wheaton, Thomas L Gentles, Julian Ayer, Leeanne E Grigg, Robert N Justo, Dorothy J Radford, Andrew Bullock, David S Celermajer, Kim Dalziel, Chris Schilling, Yves d'Udekem

2016-05-01

BACKGROUND: Despite a lack of evidence supporting the use of angiotensin-converting enzyme (ACE) inhibitors in patients with a Fon..