Combination immune checkpoint blocker inhibition to eliminate HIV latency
Grant number: 109226-58-RGRL | Funding period: 2015 - 2020
Related publications (7)
A gathering storm: HIV infection and nonalcoholic fatty liver disease in low and middle-income countries
Nitin Kapoor, Jennifer Audsley, Priscilla Rupali, Joe Sasadeusz, Thomas Paul, Nihal Thomas, Sharon R Lewin
: Despite the decreasing total incidence of liver-related deaths, liver disease remains one of the major non-AIDS causes of morbid..
PD-1 blockade potentiates HIV latency reversal ex vivo in CD4( ) T cells from ART-suppressed individuals
Remi Fromentin, Sandrina DaFonseca, Cecilia T Costiniuk, Mohamed El-Far, Francesco Andrea Procopio, Frederick M Hecht, Rebecca Hoh, Steven G Deeks, Daria J Hazuda, Sharon R Lewin, Jean-Pierre Routy, Rafick-Pierre Sekaly, Nicolas Chomont
HIV persists in latently infected CD4+ T cells during antiretroviral therapy (ART). Immune checkpoint molecules, including PD-1, a..
HIV cure research: print and online media reporting in Australia
Jennifer Power, Bianca Fileborn, Gary W Dowsett, Jayne Lucke, Graham Brown, Jeanne Ellard, Sharon R Lewin, Joseph D Tucker, Sean Slavin, Jeremy Sugarman, Sophie Hill
OBJECTIVES: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media inte..
Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals
Kersten K Koelsch, Thomas A Rasmussen, William J Hey-Nguyen, Chester Pearson, Yin Xu, Michelle Bailey, Katherine H Marks, Sarah C Sasson, Mark S Taylor, Robyn Tantau, Solange Obeid, Brad Milner, Orla Morrissey, Angie N Pinto, Kazuo Suzuki, Michael P Busch, Sheila M Keating, Philipp Kaiser, Steven Yukl, Joseph K Wong
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to significant changes to the HIV reservoir and HIV..
A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.
Leslie R Cockerham, Steven A Yukl, Kara Harvill, Ma Somsouk, Sunil K Joshi, Elizabeth Sinclair, Teri Liegler, Rebecca Hoh, Sophie Lyons, Peter W Hunt, Adam Rupert, Irini Sereti, David R Morcock, Ajantha Rhodes, Claire Emson, Marc K Hellerstein, Jacob D Estes, Sharon Lewin, Steven G Deeks, Hiroyu Hatano
BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibroti..