UNDERSTANDING THE ROLE OF SEX HORMONES IN MENTAL ILLNESS

Sex Differences in Psychosis: Focus on Animal Models.

Andrea Gogos, Maarten van den Buuse

2023-01-01

Most psychiatric illnesses, such as schizophrenia, show profound sex differences in incidence, clinical presentation, course, and ..

Characterisation of Deficits and Sex Differences in Verbal and Visual Memory/Learning in Bipolar Disorder

Andrea Gogos, Jinwon Son, Susan L Rossell, James Karantonis, Lisa S Furlong, Kim Felmingham, Tamsyn E Van Rheenen

2022-01-24

OBJECTIVE: Cognitive impairment is consistently reported in bipolar disorder (BD), but few studies have characterised which memory..

A review of sex differences in the mechanisms and drivers of overeating

RG Anversa, M Muthmainah, D Sketriene, A Gogos, P Sumithran, RM Brown

2021-09-03

Disordered eating is often associated with marked psychological and emotional distress, and severe adverse impact on quality of li..

Long-term effects of young-adult methamphetamine on dorsal raphe serotonin systems in mice: Role of brain-derived neurotrophic factor

Mauricio Sepulveda, Elizabeth E Manning, Andrea Gogos, Matthew Hale, Maarten van den Buuse

2021-04-10

To assess the long-term effects of chronic adolescent methamphetamine (METH) treatment on the serotonin system in the brain, we us..

The impact of ovariectomy and chronic estrogen treatment on gene expression in the rat cortex: Implications for psychiatric disorders

Brian Dean, Andrea Gogos

2021-03-14

Estrogens, via estrogen-mediated changes in CNS function, have been suggested to be beneficial in the treatment of several psychia..

Orexins (hypocretins): The intersection between homeostatic and hedonic feeding

Muthmainah Muthmainah, Andrea Gogos, Priya Sumithran, Robyn M Brown

2021-03-10

Orexins are hypothalamic neuropeptides originally discovered to play a role in the regulation of feeding behaviour. The broad conn..

Cortical expression of the RAPGEF1 gene in schizophrenia: investigating regional differences and suicide

Andrea Gogos, Jeehae Sun, Madhara Udawela, Andrew Gibbons, Maarten van den Buuse, Elizabeth Scarr, Brian Dean

2021-02-24

Rap guanine nucleotide exchange factor 1 (RAPGEF1) is involved in cell adhesion and neuronal migration. Previously we found lower ..

Impact of hypoxia-ischemia and dopamine treatment on dopamine receptor binding density in the preterm fetal sheep brain

FY Wong, A Gogos, N Hale, SA Ingelse, N Brew, KL Shepherd, M van den Buuse, DW Walker

2020-12-01

Dopamine is often used to treat hypotension in preterm infants who are at risk of hypoxic-ischemic (HI) brain injury due to cerebr..

The effect of 17 beta-estradiol on maternal immune activation-induced changes in prepulse inhibition and dopamine receptor and transporter binding in female rats

Alyssa Sbisa, Snezana Kusljic, Damon Zethoven, Maarten van den Buuse, Andrea Gogos

2020-09-01

Maternal immune activation (MIA) during pregnancy is associated with an increased risk of development of schizophrenia in later li..

The Impact of Removal of Ovarian Hormones on Cholinergic Muscarinic Receptors: Examining Prepulse Inhibition and Receptor Binding

Sarah S Ch'ng, Adam J Walker, Madeleine McCarthy, Thien-Kim Le, Natalie Thomas, Andrew Gibbons, Madhara Udawela, Snezana Kusljic, Brian Dean, Andrea Gogos

2020-02-01

Ovarian hormones, such as estrogens and progesterone, are known to exert beneficial effects on cognition and some psychiatric diso..

Sex differences in schizophrenia, bipolar disorder, and post-traumatic stress disorder: Are gonadal hormones the link?

Andrea Gogos, Luke J Ney, Natasha Seymour, Tamsyn E Van Rheenen, Kim L Felmingham

2019-11-01

In this review, we describe the sex differences in prevalence, onset, symptom profiles, and disease outcome that are evident in sc..

Differential effects of chronic 17 beta-oestradiol treatment on rat behaviours relevant to depression

Andrea Gogos, Madeleine McCarthy, Adam J Walker, Madhara Udawela, Andrew Gibbons, Brian Dean, Snezana Kusljic

2018-11-01

Sex differences are a prominent feature of the pathophysiology of psychiatric disorders, such as major depressive disorder, which ..

Sex differences in psychotomimetic-induced behaviours in rats

Andrea Gogos, Snezana Kusljic, Shane J Thwaites, Maarten van den Buuse

2017-03-30

Animal model studies using equal numbers of males and females are sparse in psychiatry research. Given the marked sex differences ..

Progesterone: The neglected hormone in schizophrenia? A focus on progesterone-dopamine interactions

Jeehae Sun, Adam J Walker, Brian Dean, Maarten van den Buuse, Andrea Gogos

2016-12-01

Sex differences appear to be an important factor in schizophrenia. Women with schizophrenia tend to exhibit less disease impairmen..