OPTIMIZING STROKE THERAPY - ADVANCED BRAIN IMAGING AND REPERFUSION THERAPIES
Grant number: 1111972 | Funding period: 2016 - 2020
Most stroke is due to a blocked blood vessel reducing blood flow to the brain. This research aims to optimize fast restoration of blood flow to the brain and improve patient outcomes. We will test potentially more effective clot-dissolving medication, examine potential benefits of redesigning pre-hospital ambulance transport systems and clarify the role of advanced brain imaging to maximize delivery of recently proven minimally invasive procedures to physically remove blood clots in the brain.
Related publications (4)
Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke
BCV Campbell, PJ Mitchell, L Churilov, N Yassi, TJ Kleinig, RJ Dowling, B Yan, SJ Bush, HM Dewey, V Thijs, R Scroop, M Simpson, M Brooks, H Asadi, TY Wu, DG Shah, T Wijeratne, T Ang, F Miteff, CR Levi
BACKGROUND: Intravenous infusion of alteplase is used for thrombolysis before endovascular thrombectomy for ischemic stroke. Tenec..
Strategic framework improves access to stroke reperfusion across the state of Victoria Australia
Janet E Bray, Sonia Denisenko, Bruce CV Campbell, Michael Stephenson, Jason Muller, Grant Hocking, Peter J Hand, Christopher F Bladin
BACKGROUND: In 2010, rapid access to stroke thrombolysis centres was limited in some regional areas in the Australian state of Vic..
Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection
BCV Campbell, PJ Mitchell, TJ Kleinig, HM Dewey, L Churilov, N Yassi, B Yan, RJ Dowling, MW Parsons, TJ Oxley, TY Wu, M Brooks, MA Simpson, F Miteff, CR Levi, M Krause, TJ Harrington, KC Faulder, BS Steinfort, M Priglinger
BACKGROUND: Trials of endovascular therapy for ischemic stroke have produced variable results. We conducted this study to test whe..