PREDICTING PERIOPERATIVE COGNITIVE DISORDERS IN THE ELDERLY BASED ON CARDIOVASCULAR RISK, AD RISK AND NEW BIOMARKERS
Grant number: 1102462 | Funding period: 2016 - 2019
Anaesthesia and surgery are common in the elderly and are known to lead to memory and thinking problems. Why this happens is unclear. I plan to study confusion, memory and thinking problems before and after surgery and to determine if blood or cerebrospinal fluid tests or modifying cardiovascular disease can predict this happening. This work will lead to early identification of people who are at risk of cognitive problems following anaesthesia and surgery, and ways to prevent this happening.
Related publications (1)
Association of Changes in Plasma Neurofilament Light and Tau Levels With Anesthesia and Surgery Results From the CAPACITY and ARCADIAN Studies
Lisbeth Evered, Brendan Silbert, David A Scott, Henrik Zetterberg, Kaj Blennow
Importance: Anesthesia and surgery are believed to act on the central nervous system by a fully reversible mechanism innocuous to ..