TARGETING COMMITMENT TO SEXUAL DIFFERENTIATION IN PLASMODIUM
Grant number: 1098992 | Funding period: 2016 - 2018
Efforts to control malaria in endemic areas are very often thwarted by "carriers", who have transmissible parasites in their bloodstream (called gametocytes), but who suffer no symptoms. These gametocytes serve as a reservoir ready to reinitiate disease transmission when mosquito numbers increase. This project will develop urgently needed strategies to target gametocytes, and thus block malaria transmission.
Related publications (1)
Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development
Molly Parkyn Schneider, Boyin Liu, Philipp Glock, Annika Suttie, Emma McHugh, Dean Andrew, Steven Batinovic, Nicholas Williamson, Eric Hanssen, Paul McMillan, Marion Hliscs, Leann Tilley, Matthew WA Dixon