Targeting Commitment To Sexual Differentiation In Plasmodium

Grant number: 1098992 | Funding period: 2016 - 2018

Completed

Abstract

Efforts to control malaria in endemic areas are very often thwarted by "carriers", who have transmissible parasites in their bloodstream (called gametocytes), but who suffer no symptoms. These gametocytes serve as a reservoir ready to reinitiate disease transmission when mosquito numbers increase. This project will develop urgently needed strategies to target gametocytes, and thus block malaria transmission.