BRAIN IRON IMAGING FOR ALZHEIMER’S DISEASE (AIBL-ADIRON STUDY)
Grant number: 1101533 | Funding period: 2016 - 2020
Iron accumulation in the brain is linked to Alzheimer's disease. New Magnetic Resonance Imaging scans allow us to painlessly image the brain and measure its size and iron concentration. In this project more than 330 volunteers over 60 will be scanned every 18 months over 3 years. We will determine if those subjects with higher iron concentration in their brain have a smaller brain and worse performance in this period. This will confirm a role for iron in Alzheimer's as a new treatment target.
Related publications (2)
Cerebral quantitative susceptibility mapping predicts amyloid-beta-related cognitive decline
Scott Ayton, Amir Fazlollahi, Pierrick Bourgeat, Parnesh Raniga, Amanda Ng, Yen Ying Lim, Ibrahima Diouf, Shawna Farquharson, Jurgen Fripp, David Ames, James Doecke, Patricia Desmond, Roger Ordidge, Colin L Masters, Christopher C Rowe, Paul Maruff, Victor L Villemagne, Olivier Salvado, Ashley I Bush