CIRCULATING TUMOUR DNA TO MONITOR TREATMENT RESPONSE AND RESISTANCE IN CHRONIC LYMPHOCYTIC LEUKAEMIA

Grant number: 1104549 | Funding period: 2016 - 2019

Completed

Abstract

Many cancers shed small amounts of DNA (ctDNA) into the patient’s bloodstream and recent advances in genomic technologies now allow levels of ctDNA to be accurately measured in the blood. Changes in ctDNA levels have potential to be used as specific markers of disease progression and/or response to cancer therapy. This project will evaluate if ctDNA can be used to monitor treatment responses and individualise treatment decisions in patients with chronic lymphocytic leukaemia.