Nanoelectromechanical Mass Spectrometry with Molecular Imaging

Abstract

This project aims to develop new technology to enable simultaneous measurement of the mass and conformation of single molecules. Mass spectrometry and high-resolution microscopy are independent analytical tools used widely to characterise the chemical and physical properties of molecules. This project aims to develop new technology based on advanced nanoelectromechanical systems that combines the capabilities of these complementary instruments. This would enable synchronous measurement of molecular mass and conformation with nanometre resolution. In contrast to current mass spectrometry, this technology could be operated in fluid and detect neutral species. This significant change in capabil..

Related publications (2)

Fabrication of a Three-Dimensional Plasmon Ruler Using an Atomic Force Microscope

Jianing Lu, Shaoding Liu, Sean SE Collins, Linlong Tang, Xingzhan Wei, Paul Mulvaney

2019-08-15

We have assembled a three-dimensional (3D) plasmon ruler using an atomic force microscope (AFM) tip to manipulate single gold nano..

Vibrational coupling in plasmonic molecules

Chongyue Yi, Pratiksha D Dongare, Man-Nung Su, Wenxiao Wang, Debadi Chakraborty, Fangfang Wen, Wei-Shun Chang, John E Sader, Peter Nordlander, Naomi J Halas, Stephan Link

2017-10-01

Plasmon hybridization theory, inspired by molecular orbital theory, has been extremely successful in describing the near-field cou..