Shape-Shifting Molecules: Photoisomerization Action Spectroscopy
Grant number: DP160100474 | Funding period: 2016 - 2020
This project aims to examine molecules that change shape in response to light in order to gain insight into the biological processes they control. Many biological systems, including the human visual apparatus and bacterial photosynthesis, depend on molecules that change shape in response to light. The project plans to probe shape-shifting molecules with laser light while they are propelled through gas by an electric field. Light-induced changes in molecular shape produce detectable variations in drift speed. The ensuing knowledge would help calibrate computational approaches for predicting molecular function. It would also establish foundations for understanding essential biological molecule..View full description
Related publications (11)
Near-infrared reversible photoswitching of an isolated azobenzene-stilbene dye
Eduardo Carrascosa, James N Bull, Jack T Buntine, Gabriel da Silva, Paulo F Santos, Evan J Bieske
Photoswitching of a charged azobenzene-stilbene dye is investigated through laser excitation in a tandem ion mobility mass spectro..
Photoinitiated Intramolecular Proton Transfer in Deprotonated para-Coumaric Acid
James N Bull, Gabriel da Silva, Michael S Scholz, Eduardo Carrascosa, Evan J Bieske
Deprotonated para-coumaric acid is commonly considered as a model for the chromophore in photoactive yellow protein, which undergo..
Ion mobility action spectroscopy of flavin dianions reveals deprotomer-dependent photochemistry
James N Bull, Eduardo Carrascosa, Linda Giacomozzi, Evan J Bieske, Mark H Stockett
The intrinsic optical properties and photochemistry of flavin adenine dinucleotide (FAD) dianions are investigated using a combina..
A strong cis-effect in an imidazole/imidazolium substituted alkene
Dayne C Georgiou, Mohammad A Haghighatbin, Conor F Hogan, Michael S Scholz, James Bull, Evan J Bieske, David JD Wilson, Jason L Dutton
We report the first example of an alkene with two carbon‐bound substituents (imidazole and imidazolium rings) where the Z‐isomer h..