BIO-METROLOGY AND MODELLING OF A COMPLEX SYSTEM: THE MALARIA PARASITE (GEORGINA SWEET FUND)
Grant number: FL150100106 | Funding period: 2016 - 2021
This fellowship project aims to develop a cross-disciplinary program to measure, model and manipulate a complex cellular system — sexual differentiation of the human malaria parasite. Combining life and physical sciences with powerful imaging techniques, the project seeks to develop quantitative biochemical, biophysical and modelling techniques to probe a complex system in a way previously not possible. It expects to integrate and correlate thousands of measurements of the dynamic processes inside cells and use these datasets to generate rigorous and sophisticated mathematical models that can predict drivers of commitment for transformation of the parasite to a sexual phase in preparation fo..View full description
Related publications (1)
A new Python library to analyse skeleton images confirms malaria parasite remodelling of the red blood cell membrane skeleton
Juan Nunez-Iglesias, Adam J Blanch, Oliver Looker, Matthew W Dixon, Leann Tilley
We present Skan (Skeleton analysis), a Python library for the analysis of the skeleton structures of objects. It was inspired by t..