ESTABLISHING THE MAXIMUM SAFE STIMULATION PARAMETERS FOR PLATINUM COCHLEAR IMPLANT ELECTRODE ARRAYS.(GRANT11829653 )
Grant number: 1R01DC015031-01/9010653 | Funding period: 2015 - 2021
Related publications (7)
Platinum dissolution and tissue response following long-term electrical stimulation at high charge densities
Robert K Shepherd, Paul M Carter, Ashley N Dalrymple, Ya Lang Enke, Andrew K Wise, Trung Nguyen, James Firth, Alex Thompson, James B Fallon
OBJECTIVE: Established guidelines for safe levels of electrical stimulation for neural prostheses are based on a limited range of ..
Chronic intracochlear electrical stimulation at high charge densities: reducing platinum dissolution
Robert K Shepherd, Paul M Carter, Ya Lang Enke, Alex Thompson, Brianna Flynn, Ella P Trang, Ashley N Dalrymple, James B Fallon
OBJECTIVE: Cochleae of long-term cochlear implant users have shown evidence of particulate platinum (Pt) corroded from the surface..
Chronic intracochlear electrical stimulation at high charge densities results in platinum dissolution but not neural loss or functional changes in vivo
Robert K Shepherd, Paul M Carter, Ya Lang Enke, Andrew K Wise, James B Fallon
OBJECTIVE: Although there are useful guidelines defining the boundary between damaging and non-damaging electrical stimulation the..
Structural and Ultrastructural Changes to Type I Spiral Ganglion Neurons and Schwann Cells in the Deafened Guinea Pig Cochlea
Andrew K Wise, Remy Pujol, Thomas G Landry, James B Fallon, Robert K Shepherd
Sensorineural hearing loss is commonly caused by damage to cochlear sensory hair cells. Coinciding with hair cell degeneration, th..
Evaluation of focused multipolar stimulation for cochlear implants: a preclinical safety study
Robert K Shepherd, Andrew K Wise, Ya Lang Enke, Paul M Carter, James B Fallon
OBJECTIVE: Cochlear implants (CIs) have a limited number of independent stimulation channels due to the highly conductive nature o..