NEXT GENERATION CYBERNETICS: LONG TERM CARBON FIBRE DUAL STIMULATION / RECORDING ELECTRODE ARRAYS FOR CLOSED LOOP NEURAL IMPLANTS

Grant number: 1101717 | Funding period: 2016 - 2021

Completed

Abstract

Electrodes implanted in the brain have enormous potential for treating a range of conditions from epilepsy to control of prosthetics for patients with limb loss. Currently, the electrodes used in such system fail rapidly because they are rejected by the body. We aim to use diamond with ultra-fine carbon fibre electrodes to make arrays that are invisible to the human immune system. Such arrays will function for the lifetime of the patient without needing replacement.

Related publications (25)

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Minimizing axon bundle activation of retinal ganglion cells with oriented rectangular electrodes.

Wei Tong, Maryam Hejazi, David J Garrett, Timothy Esler, Steven Prawer, Hamish Meffin, Michael Ibbotson

2020-06-17

OBJECTIVE: Retinal prostheses aim to restore vision in patients with retinal degenerative diseases, such as age-related macular de..

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Stimulation Strategies for Improving the Resolution of Retinal Prostheses.

Wei Tong, Hamish Meffin, David J Garrett, Michael R Ibbotson

2020-03-26

Electrical stimulation using implantable devices with arrays of stimulating electrodes is an emerging therapy for neurological dis..

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Electrical receptive fields of retinal ganglion cells: Influence of presynaptic neurons

Matias I Maturana, Nicholas V Apollo, David J Garrett, Tatiana Kameneva, Shaun L Cloherty, David B Grayden, Anthony N Burkitt, Michael R Ibbotson, Hamish Meffin

2018-02-01

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Wireless induction coils embedded in diamond for power transfer in medical implants

Md Kabir Uddin Sikder, James Fallon, Mohit N Shivdasani, Kumaravelu Ganesan, Peter Seligman, David J Garrett

2017-12-01

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Neural Responses to Multielectrode Stimulation of Healthy and Degenerate Retina

Kerry J Halupka, Carla J Abbott, Yan T Wong, Shaun L Cloherty, David B Grayden, Anthony N Burkitt, Evgeni N Sergeev, Chi D Luu, Alice Brandli, Penelope J Allen, Hamish Meffin, Mohit N Shivdasani

2017-07-01

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Diamond Devices for High Acuity Prosthetic Vision

Arman Ahnood, Hamish Meffin, David J Garrett, Kate Fox, Kumaravelu Ganesan, Alastair Stacey, Nicholas V Apollo, Yan T Wong, Samantha G Lichter, William Kentler, Omid Kavehei, Ursula Greferath, Kirstan A Vessey, Michael R Ibbotson, Erica L Fletcher, Anthony N Burkitt, Steven Prawer

2017-02-01

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Prediction of cortical responses to simultaneous electrical stimulation of the retina

Kerry J Halupka, Mohit N Shivdasani, Shaun L Cloherty, David B Grayden, Yan T Wong, Anthony N Burkitt, Hamish Meffin

2017-02-01

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Brazing techniques for the fabrication of biocompatible carbon-based electronic devices

Nicholas V Apollo, Desmond Lau, Arman Ahnood, Alastair Stacey, Kumaravelu Ganesan, Samantha G Lichter, Kate Fox, Javad Foroughi, Hamish Meffin, Gordon G Wallace, Ray Baughman, Steven Prawer, David J Garrett

2016-10-01

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Optimizing growth and post treatment of diamond for high capacitance neural interfaces

Wei Tong, Kate Fox, Akram Zamani, Ann M Turnley, Kumaravelu Ganesan, Arman Ahnood, Rosemary Cicione, Hamish Meffin, Steven Prawer, Alastair Stacey, David J Garrett

2016-10-01

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Diamond for neural interfacing: A review

David J Garrett, Wei Tong, David A Simpson, Hamish Meffin

2016-06-01

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Spectral distribution of local field potential responses to electrical stimulation of the retina

Yan T Wong, Kerry Halupka, Tatiana Kameneva, Shaun L Cloherty, David B Grayden, Anthony N Burkitt, Hamish Meffin, Mohit N Shivdasani

2016-06-01

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A Simple and Accurate Model to Predict Responses to Multi-electrode Stimulation in the Retina

Matias I Maturana, Nicholas V Apollo, Alex E Hadjinicolaou, David J Garrett, Shaun L Cloherty, Tatiana Kameneva, David B Grayden, Michael R Ibbotson, Hamish Meffin

2016-04-01

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Development of a Magnetic Attachment Method for Bionic Eye Applications

Kate Fox, Hamish Meffin, Owen Burns, Carla J Abbott, Penelope J Allen, Nicholas L Opie, Ceara McGowan, Jonathan Yeoh, Arman Ahnood, Chi D Luu, Rosemary Cicione, Alexia L Saunders, Michelle McPhedran, Lisa Cardamone, Joel Villalobos, David J Garrett, David AX Nayagam, Nicholas V Apollo, Kumaravelu Ganesan, Mohit N Shivdasani

2016-03-01

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Retinal ganglion cells: mechanisms underlying depolarization block and differential responses to high frequency electrical stimulation of ON and OFF cells

T Kameneva, MI Maturana, AE Hadjinicolaou, SL Cloherty, MR Ibbotson, DB Grayden, AN Burkitt, H Meffin

2016-02-01

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A computational model of orientation-dependent activation of retinal ganglion cells

Timothy Esler, Anthony N Burkitt, David B Grayden, Robert R Kerr, Bahman Tahayori, Hamish Meffin

2016-01-01

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In vivo biocompatibility of boron doped and nitrogen included conductive-diamond for use in medical implants

David J Garrett, Alexia L Saunders, Ceara McGowan, Joscha Specks, Kumaravelu Ganesan, Hamish Meffin, Richard A Williams, David AX Nayagam

2016-01-01

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Spatial phase sensitivity of complex cells in primary visual cortex depends on stimulus contrast

H Meffin, MA Hietanen, SL Cloherty, MR Ibbotson

2015-12-01

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Prosthetic vision: devices, patient outcomes and retinal research

Alex E Hadjinicolaou, Hamish Meffin, Matias I Maturana, Shaun L Cloherty, Michael R Ibbotson

2015-09-01

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Hermetic diamond capsules for biomedical implants enabled by gold active braze alloys

Samantha G Lichter, Mathilde C Escudie, Alastair D Stacey, Kumaravelu Ganesan, Kate Fox, Arman Ahnood, Nicholas V Apollo, Dunstan C Kua, Aaron Z Lee, Ceara McGowan, Alexia L Saunders, Owen Burns, David AX Nayagam, Richard A Williams, David J Garrett, Hamish Meffin, Steven Prawer

2015-06-01

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Spike history neural response model

Tatiana Kameneva, Miganoosh Abramian, Daniele Zarelli, Dragan Nesic, Anthony N Burkitt, Hamish Meffin, David B Grayden

2015-06-01

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Ultrananocrystalline diamond-CMOS device integration route for high acuity retinal prostheses

A Ahnood, MC Escudie, R Cicione, CD Abeyrathne, K Ganesan, KE Fox, DJ Garrett, A Stacey, NV Apollo, SG Lichter, CDL Thomas, N Tran, H Meffin, S Prawer

2015-06-01

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Broadband Onset Inhibition Can Suppress Spectral Splatter in the Auditory Brainstem

Martin J Spencer, David AX Nayagam, Janine C Clarey, Antonio G Paolini, Hamish Meffin, Anthony N Burkitt, David B Grayden

2015-05-15

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The bionic eye: A review of multielectrode arrays

K Fox, O Burns, DJ Garrett, MN Shivdasani, H Meffin

2015-01-01

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The effects of temperature changes on retinal ganglion cell responses to electrical stimulation

MI Maturana, NV Apollo, DJ Garrett, T Kameneva, H Meffin, MR Ibbotson, SL Cloherty, D GRAYDEN

2015-01-01

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Fabrication of planarised conductively patterned diamond for bio-applications

Wei Tong, Kate Fox, Kumaravelu Ganesan, Ann M Turnley, Olga Shimoni, Phong A Tran, Alexander Lohrmann, Thomas McFarlane, Arman Ahnood, David J Garrett, Hamish Meffin, Neil M O'Brien-Simpson, Eric C Reynolds, Steven Prawer

2014-10-01