Determining The Contribution Of Orexin Receptor Subtypes To Sleep Architecture

Grant number: 1105284 | Funding period: 2016 - 2019

Completed

Abstract

Sleep is an essential process that follows a regular pattern every night. The brain orexin system is a promising new target for sleep-inducing drugs; however it is not clear how best to manipulate this system to reproduce the cycles of sleep necessary to receive all the benefits sleep has to offer. This project will elucidate the contribution of the different components of the orexin system to the characteristics of sleep. This will facilitate the development of better treatments for insomnia.