High Throughput, Inexpensive Methods For Typing Immune System Genes And Assessing Their Role In Human Disease Worldwide

Abstract

Immune system genes are strongly implicated in many infectious and autoimmune diseases, as well as cancer. Some of these genes have many possible types due to natural selection in response to pathogens. This variability makes typing these genes very expensive. Developing accurate and inexpensive methods to type these genes is vital in understanding the role they play in susceptibility and progression of disease and will be important for the development of better diagnostic tests and treatments.

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2017-02-01