Optimising the efficacy of mycoplasma vaccines in the field
Grant number: LP160101105 | Funding period: 2016 - 2021
This project intends to examine the effect of antibiotic treatment, killed vaccines and immunosuppressive viruses on the protective immunity induced by a model novel vaccine against the important poultry pathogen Mycoplasma gallisepticum. The continued circulation of pathogenic mycoplasmas in intensively managed animals is a major animal health problem. Live attenuated vaccines could reduce disease, but we have limited understanding of the best conditions for their use. This project will generate data to guide both use and development of live mycoplasma vaccines. It is expected to have significant impacts on animal health, welfare and production, and public health by reducing the use of anti..View full description
Related publications (3)
Effects of immunosuppression on the efficacy of vaccination against Mycoplasma gallisepticum infection in chickens
Sathya N Kulappu Arachchige, Anna Kanci Condello, Ling Zhu, Pollob K Shil, Kelly A Tivendale, Gregory J Underwood, Amir H Noormohammadi, Glenn F Browning, Nadeeka K Wawegama
Immunosuppression can increase the susceptibility of chickens to other disease-causing pathogens and interfere with the efficacy o..
Mucosal immune responses in the trachea after chronic infection with Mycoplasma gallisepticum in unvaccinated and vaccinated mature chickens
Sathya N Kulappu Arachchige, Nadeeka K Wawegama, Mauricio JC Coppo, Habtamu B Derseh, Paola K Vaz, Anna Kanci Condello, Oluwadamilola S Omotainse, Amir H Noormohammadi, Glenn F Browning
Tracheitis associated with the chronic respiratory disease in chickens caused by Mycoplasma gallisepticum is marked by infiltratio..
Differential Response of the Chicken Trachea to Chronic Infection with Virulent Mycoplasma gallisepticum Strain Ap3AS and Vaxsafe MG (Strain ts-304): a Transcriptional Profile
Sathya N Kulappu Arachchige, Neil D Young, Pollob K Shil, Alistair R Legione, Anna Kanci Condello, Glenn F Browning, Nadeeka K Wawegama
Mycoplasma gallisepticum is the primary etiological agent of chronic respiratory disease in chickens. Live attenuated vaccines are..