MULTIDISCIPLINARY TRANSLATIONAL RESEARCH TO ADDRESS SOCIAL DISPARITIES IN OSTEOPOROSIS: UNDERSTANDING THE SOCIAL CONTEXT OF BIOLOGICAL MECHANISMS
Grant number: 1107510 | Funding period: 2016 - 2020
Osteoporosis (OP) prevalence is greater for disadvantaged groups, as are less healthy lifestyles. Whilst reasons for this social gradient of OP are unknown, some biological phenomena are influenced by lifestyle factors. I will provide novel evidence about biological mechanisms underlying the social gradient of OP (epigenetics), and, using that information, engage disadvantaged communities in multidisciplinary discussions to inform effective public health interventions (community engagement).
Related publications (30)
Health service use pathways associated with recovery of quality of life at 12-months for individual fracture sites: Analyses of the International Costs and Utilities Related to Osteoporotic fractures Study (ICUROS).
Jason Talevski, Kerrie M Sanders, Ljoudmila Busija, Alison Beauchamp, Gustavo Duque, Fredrik Borgström, John A Kanis, Axel Svedbom, Amanda L Stuart, Sharon Brennan-Olsen
PURPOSE: We aimed to identify combinations of health service use specific to each major osteoporotic fracture (MOF) site - hip, di..
Walking Speed and Muscle Mass Estimated by the D3-Creatine Dilution Method Are Important Components of Sarcopenia Associated With Incident Mobility Disability in Older Men: A Classification and Regression Tree Analysis
Jesse Zanker, Sheena Patel, Terri Blackwell, Kate Duchowny, Sharon Brennan-Olsen, Steven R Cummings, William J Evans, Eric S Orwoll, David Scott, Sara Vogrin, Jane A Cauley, Gustavo Duque, Peggy M Cawthon
OBJECTIVES: It is unknown whether muscle mass measured by the D3-creatine dilution method is a superior predictor of incident mobi..
Gestational Vitamin D and Offspring Bone Measures: Is the Association Independent of Maternal Bone Quality?
Natalie K Hyde, Sharon L Brennan-Olsen, John D Wark, Sarah M Hosking, Julie A Pasco
Previously we have reported an association between maternal vitamin D and offspring bone as measured by dual-energy X-ray absorpti..
Health Service Use and Quality of Life Recovery 12 Months Following Major Osteoporotic Fracture: Latent Class Analyses of the International Costs and Utilities Related to Osteoporotic Fractures Study (ICUROS)
Jason Talevski, Kerrie M Sanders, Ljoudmila Busija, Alison Beauchamp, Gustavo Duque, Fredrik Borgstrom, John A Kanis, Axel Svedbom, Catherine Connaughton, Amanda L Stuart, Sharon L Brennan-Olsen
Major osteoporotic fractures (MOFs) are associated with a rapid decline in health-related quality of life (HRQoL); however, there ..
Bone health in bipolar disorder: a study protocol for a case-control study in Australia
Lana J Williams, Amanda L Stuart, Michael Berk, Sharon L Brennan-Olsen, Jason M Hodge, Stephanie Cowdery, Vinoomika Chandrasekaran, Julie A Pasco
INTRODUCTION: Little is known about the bone health of adults with bipolar disorder, aside from evidence purporting bone deficits ..
The epidemiology of hip fractures across western Victoria, Australia
Kara L Holloway, Muhammad A Sajjad, Mohammadreza Mohebbi, Mark A Kotowicz, Patricia M Livingston, Mustafa Khasraw, Sharon Hakkennes, Trisha L Dunning, Susan Brumby, Richard S Page, Daryl Pedler, Alasdair Sutherland, Svetha Venkatesh, Sharon L Brennan-Olsen, Lana J Williams, Julie A Pasco
Geographic region, socioeconomic position and the utilisation of primary total joint replacement for hip or knee osteoarthritis across western Victoria: a cross-sectional multilevel study of the Australian Orthopaedic Association National Joint Replacement Registry
Sharon Brennan-Olsen, Sara Vogrin, Kara L Holloway, Richard S Page, Muhammad A Sajjad, Mark A Kotowicz, Patricia M Livingston, Mustafa Khasraw, Sharon Hakkennes, Trish L Dunning, Susan Brumby, Daryl Pedler, Alasdair Sutherland, Svetha Venkatesh, Lana J Williams, Gustavo Duque, Julie A Pasco
Personality disorder is an excess risk factor for physical multimorbidity among women with mental state disorders
Shae E Quirk, Amanda L Stuart, Michael Berk, Julie A Pasco, Sharon L Brennan Olsen, Heli Koivumaa-Honkanen, Risto Honkanen, Pyry S Lukkala, Andrew M Chanen, Mark Kotowicz, Lana J Williams
Prevalence of arthritis according to age, sex and socioeconomic status in six low and middle income countries: analysis of data from the World Health Organization study on global AGEing and adult health (SAGE) Wave 1
Sharon L Brennan-Olsen, S Cook, MT Leech, SJ Bowe, P Kowal, N Naidoo, N Ackerman, RS Page, SM Hosking, JA Pasco, M Mohebbi
An Australian Indigenous community-led suicide intervention skills training program: community consultation findings
Bushra Nasir, Steve Kisely, Leanne Hides, Geetha Ranmuthugala, Sharon Brennan-Olsen, Geoffrey C Nicholson, Neeraj S Gill, Noel Hayman, Srinivas Kondalsamy-Chennakesavan, Maree Toombs
Fractures in indigenous compared to non-indigenous populations: A systematic review of rates and aetiology.
Sharon L Brennan-Olsen, Sara Vogrin, William D Leslie, Rita Kinsella, Maree Toombs, Gustavo Duque, Sarah M Hosking, Kara L Holloway, Brianna J Doolan, Lana J Williams, Richard S Page, Julie A Pasco, Shae E Quirk
BACKGROUND: Compared to non-indigenous populations, indigenous populations experience disproportionately greater morbidity, and a ..
THE AGEING, CHRONIC DISEASE AND INJURY STUDY: EPIDEMIOLOGY OF HIP FRACTURES ACROSS WESTERN VICTORIA, AUSTRALIA
K Holloway, MA Sajjad, M Mohcbbi, M Kotowicz, P Livingston, M Khasraw, S Hakkennes, T Dunning, S Brumby, R Page, D Pedler, A Sutherland, S Venkatesh, S Brennan-Olsen, L Williams, J Pasco
Few geographic and socioeconomic variations exist in primary total shoulder arthroplasty: a multi-level study of Australian registry data
Sharon L Brennan-Olsen, Richard S Page, Stephen E Lane, Michelle Lorimer, Rachelle Buchbinder, Richard H Osborne, Julie A Pasco, Anita Wluka, Kerrie M Sanders, Peter R Ebeling, Stephen E Graves
DNA methylation and the social gradient of osteoporotic fracture: A conceptual model
Sharon L Brennan-Olsen, Richard S Page, Michael Berk, Jose A Riancho, William D Leslie, Scott G Wilson, Karen L Saban, Linda Janusek, Julie A Pasco, Jason M Hodge, Shae E Quirk, Natalie K Hyde, Sarah M Hosking, Lana J Williams
Ageing, chronic disease and injury: a study in western Victoria (Australia)
M Amber Sajjad, Kara L Holloway, Mark A Kotowicz, Patricia M Livingston, Mustafa Khasraw, Sharon Hakkenes, Trisha L Dunning, Susan Brumby, Richard S Page, Daryl Pedler, Alasdair Sutherland, Svetha Venkatesh, Sharon L Brennan-Olsen, Lana J Williams, Julie A Pasco