PERSONALISED MEDICINE FOR MITOCHONDRIAL DISORDERS: TARGETING PATHOGENIC MECHANISMS

Grant number: 1107094 | Funding period: 2016 - 2020

Completed

Abstract

Mitochondria are our cellular power plants that burn sugars, fats and proteins to generate energy. Each week in Australia a child is born with a mitochondrial disorder. Many of these children die in the first years of life and most suffer from severe disease, particularly affecting their brain and/or heart. We will use stem cell models to better understand the basic biology of these disorders and to develop targeted therapies to improve the outcomes for affected patients.

Related publications (10)

University of Melbourne Researchers