ENHANCING DISEASE VECTOR BIOSECURITY THROUGH HIGH DENSITY MOLECULAR MARKERS

Unbiased population heterozygosity estimates from genome-wide sequence data

Thomas L Schmidt, Moshe-Elijah Jasper, Andrew R Weeks, Ary A Hoffmann

2021-07-01

Heterozygosity is a metric of genetic variability frequently used to inform the management of threatened taxa. Estimating observed..

Improving mosquito control strategies with population genomics.

Thomas L Schmidt, Nancy M Endersby-Harshman, Ary A Hoffmann

2021-05-29

Mosquito control strategies increasingly apply knowledge from population genomics research. This review highlights recent applicat..

Wolbachia strain wAlbB maintains high density and dengue inhibition following introduction into a field population of Aedes aegypti

Noor Afizah Ahmad, Maria-Vittoria Mancini, Thomas H Ant, Julien Martinez, Ghazali MR Kamarul, Wasi A Nazni, Ary A Hoffmann, Steven P Sinkins

2021-02-15

Aedes aegypti mosquitoes carrying the wAlbB Wolbachia strain show a reduced capacity to transmit dengue virus. wAlbB has been intr..

Infertility and fecundity loss of Wolbachia-infected Aedes aegypti hatched from quiescent eggs is expected to alter invasion dynamics

Meng-Jia Lau, Perran A Ross, Ary A Hoffmann

2021-02-01

The endosymbiotic bacterium Wolbachia shows viral blocking in its mosquito host, leading to its use in arboviral disease control. ..

Spatial population genomics of a recent mosquito invasion

Thomas L Schmidt, T Swan, Jessica Chung, Stephan Karl, Samuel Demok, Qiong Yang, Matt A Field, Mutizwa Odwell Muzari, Gerhard Ehlers, Mathew Brugh, Rodney Bellwood, Peter Horne, Thomas R Burkot, Scott Ritchie, Ary A Hoffmann

2021-01-24

Population genomic approaches can characterize dispersal across a single generation through to many generations in the past, bridg..

Wolbachia Genome Stability and mtDNA Variants in Aedes aegypti Field Populations Eight Years after Release

Bixing Huang, Qiong Yang, Ary A Hoffmann, Scott A Ritchie, Andrew F van den Hurk, David Warrilow

2020-10-23

A dengue suppression strategy based on release of Aedes aegypti mosquitoes infected with the bacterium Wolbachia pipientis is bein..

Impacts of Low Temperatures on Wolbachia (Rickettsiales: Rickettsiaceae)-Infected Aedes aegypti (Diptera: Culicidae)

Meng-Jia Lau, Perran A Ross, Nancy M Endersby-Harshman, Ary A Hoffmann

2020-09-01

In recent decades, the occurrence and distribution of arboviral diseases transmitted by Aedes aegypti mosquitoes has increased. In..

Frequency of kdr mutations in the voltage-sensitive sodium channel (V-SSC) gene in Aedes aegypti from Yogyakarta and implications for Wolbachia-infected mosquito trials

Juli Rochmijati Wuliandari, Ary A Hoffmann, Warsito Tantowijoyo, Nancy M Endersby-Harshman

2020-08-24

Background In the inner city of Yogyakarta, Indonesia, insecticide resistance is expected in the main dengue vector, Aedes aegypti..

Heterogeneous genetic invasions of three insecticide resistance mutations in Indo-Pacific populations of Aedes aegypti (L.)

Nancy M Endersby-Harshman, Thomas L Schmidt, Jessica Chung, Anthony van Rooyen, Andrew R Weeks, Ary A Hoffmann

2020-04-21

Nations throughout the Indo-Pacific region use pyrethroid insecticides to control Aedes aegypti, the mosquito vector of dengue, of..

Persistent deleterious effects of a deleterious Wolbachia infection

Perran A Ross, Jason K Axford, Ashley G Callahan, Kelly M Richardson, Ary A Hoffmann

2020-04-03

Wolbachia are being used to reduce dengue transmission by Aedes aegypti mosquitoes around the world. To date releases have mostly ..

An elusive endosymbiont: Does Wolbachia occur naturally in Aedes aegypti?

Perran A Ross, Ashley G Callahan, Qiong Yang, Moshe Jasper, Mohd AK Arif, Ahmad Noor Afizah, Wasi A Nazni, Ary A Hoffmann

2020-02-01

Wolbachia are maternally inherited endosymbiotic bacteria found within many insect species. Aedes mosquitoes experimentally infect..

Heatwaves cause fluctuations in wMel Wolbachia densities and frequencies in Aedes aegypti

Perran A Ross, Jason K Axford, Qiong Yang, Kyran M Staunton, Scott A Ritchie, Kelly M Richardson, Ary A Hoffmann

2020-01-01

Aedes aegypti mosquitoes infected with the wMel strain of Wolbachia are being released into natural mosquito populations in the tr..

Establishment of Wolbachia Strain wAlbB in Malaysian Populations of Aedes aegypti for Dengue Control

Wasi A Nazni, Ary A Hoffmann, Ahmad NoorAfizah, Yoon Ling Cheong, Maria V Mancini, Nicholas Golding, Ghazali MR Kamarul, Mohd AK Arif, Hasim Thohir, Halim NurSyamimi, M Zabari ZatilAqmar, Mazni NurRuqqayah, Amran NorSyazwani, Azmi Faiz, Francis-Rudin MN Irfan, Subramaniam Rubaaini, Nasir Nuradila, Nasir MN Nizam, Saidin M Irwan, Nancy M Endersby-Harshman

2019-12-16

Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia ..

Persistent deleterious effects of an unstable deleteriousWolbachiainfection

Perran Ross, Jason Axford, Ashley Callahan, Kelly Richardson, Ary Hoffmann

2019-11-25

Wolbachia are being used to reduce dengue transmission by Aedes aegypti mosquitoes around the world. To date releases have mostly ..

A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions

Moshe E Jasper, Qiong Yang, Perran A Ross, Nancy Endersby-Harshman, Nicholas Bell, Ary A Hoffmann

2019-11-20

With Wolbachia-based arbovirus control programs being scaled and operationalised around the world, cost effective and reliable det..

Does membrane feeding compromise the quality of Aedes aegypti mosquitoes?

Perran A Ross, Meng-Jia Lau, Ary A Hoffmann

2019-11-06

Modified Aedes aegypti mosquitoes are being mass-reared for release in disease control programs around the world. Releases involvi..

An elusive endosymbiont: Does Wolbachia occur naturally in Aedes aegypti?

Perran Ross, Ashley Callahan, Qiong Yang, Moshe Jasper, AKM Arif, A Noor Afizah, WA Nazni, Ary Hoffmann

2019-10-17

Wolbachia are maternally-inherited endosymbiotic bacteria found within many insect species. Aedes mosquitoes experimentally infect..

Establishment of Wolbachia strain wAlbB in Malaysian populations of Aedes aegypti for dengue control

WA Nazni, AA Hoffmann, A Noor Afizah, YL Cheong, MV Mancini, N Golding, MRG Kamarul, AKM Arif, H Thohir, HS Nur Syamimi, MZ Nur Zatil Aqmar, MM Nur Ruqqayah, A Siti Nor Syazwani, A Faiz, MNFR Irfan, S Rubaaini, N Nuradila, MMN Nizam, MS Mohamad Irwan, NM Endersby-Harshman

2019-09-19

Dengue has enormous health impacts globally. A novel approach to decrease dengue incidence involves the introduction of Wolbachia ..

Heterogeneous genetic invasions of three insecticide resistance mutations in Indo-Pacific populations of Aedes aegypti (L.)

Nancy Endersby-Harshman, Thomas Schmidt, Jessica Chung, Anthony van Rooyen, Andrew Weeks, Ary Hoffmann

2019-09-16

Nations throughout the Indo-Pacific region use pyrethroid insecticides to control Aedes aegypti , the mosquito vector of dengue, o..

A genomic approach to inferring kinship reveals limited intergenerational dispersal in the yellow fever mosquito

Moshe Jasper, Thomas L Schmidt, Nazni W Ahmad, Steven P Sinkins, Ary A Hoffmann

2019-09-01

Understanding past dispersal and breeding events can provide insight into ecology and evolution and can help inform strategies for..

A LAMP assay for the rapid and robust assessment of Wolbachia infection in Aedes aegypti under field and laboratory conditions

Moshe Jasper, Qiong Yang, Perran Ross, Nancy Endersby-Harshman, Nicholas Bell, Ary Hoffmann

2019-08-09

Abstract With Wolbachia -based arbovirus control programs being scaled and operationalised around the world, cost effective and re..

A genomic approach to inferring kinship reveals limited intergenerational dispersal in the yellow fever mosquito

Moshe Jasper, Thomas Schmidt, Nazni Ahmad, Steven Sinkins, Ary Hoffmann

2019-05-14

Understanding past dispersal and breeding events can provide insight into ecology and evolution, and can help inform strategies fo..

Life History Effects Linked to an Advantage for wAu Wolbachia in Drosophila

Li-Jun Cao, Weibin Jiang, Ary A Hoffmann

2019-05-01

Wolbachia endosymbiont infections can persist and spread in insect populations without causing apparent effects on reproduction of..

Loss of cytoplasmic incompatibility in Wolbachia-infected Aedes aegypti under field conditions

Perran A Ross, Scott A Ritchie, Jason K Axford, Ary A Hoffmann

2019-04-01

Wolbachia bacteria are now being introduced into Aedes aegypti mosquito populations for dengue control. When Wolbachia infections ..

Contrasting Patterns of Virus Protection and Functional Incompatibility Genes in Two Conspecific Wolbachia Strains from Drosophila pandora

Angelique K Asselin, Simon Villegas-Ospina, Ary A Hoffmann, Jeremy C Brownlie, Karyn N Johnson

2019-03-01

Wolbachia infections can present different phenotypes in hosts, including different forms of reproductive manipulation and antivir..

Cross-Generational Effects of Heat Stress on Fitness and Wolbachia Density in Aedes aegypti Mosquitoes

Isabelle Jia-Hui Foo, Ary A Hoffmann, Perran A Ross

2019-03-01

Aedes aegypti mosquitoes infected with Wolbachia symbionts are now being released into the field to control the spread of pathogen..

Establishment of wMel Wolbachia in Aedes aegypti mosquitoes and reduction of local dengue transmission in Cairns and surrounding locations in northern Queensland, Australia.

Peter A Ryan, Andrew P Turley, Geoff Wilson, Tim P Hurst, Kate Retzki, Jack Brown-Kenyon, Lauren Hodgson, Nichola Kenny, Helen Cook, Brian L Montgomery, Christopher J Paton, Scott A Ritchie, Ary A Hoffmann, Nicholas P Jewell, Stephanie K Tanamas, Katherine L Anders, Cameron P Simmons, Scott L O'Neill

2019-01-01

Background: The wMel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and subsequently shown in ..

No detectable effect of Wolbachia wMel on the prevalence and abundance of the RNA virome of Drosophila melanogaster

Mang Shi, Vanessa L White, Timothy Schlub, John-Sebastian Eden, Ary A Hoffmann, Edward C Holmes

2018-07-25

Wolbachia is an endosymbiotic bacterium that can block viral infections in arthropods, generating interest in its potential to con..

Rates and Patterns of Laboratory Adaptation in (Mostly) Insects

Ary A Hoffmann, Perran A Ross

2018-04-01

Insects and other invertebrates can readily adapt to a range of environmental conditions and these include conditions used in arti..

Rapid Global Spread of wRi-like Wolbachia across Multiple Drosophila

Michael Turelli, Brandon S Cooper, Kelly M Richardson, Paul S Ginsberg, Brooke Peckenpaugh, Chenling X Antelope, Kevin J Kim, Michael R May, Antoine Abrieux, Derek A Wilson, Michael J Bronski, Brian R Moore, Jian-Jun Gao, Michael B Eisen, Joanna C Chiu, William R Conner, Ary A Hoffmann

2018-03-19

Maternally transmitted Wolbachia, Spiroplasma, and Cardinium bacteria are common in insects [1], but their interspecific spread is..

Wolbachia-induced loss of male fertility is likely related to branch chain amino acid biosynthesis and iLvE in Laodelphax striatellus

Jia-Fei Ju, Ary A Hoffmann, Yan-Kai Zhang, Xing-Zhi Duan, Yan Guo, Jun-Tao Gong, Wen-Chao Zhu, Xiao-Yue Hong

2017-06-01

Wolbachia are endosymbionts that infect many species of arthropods and nematodes. Wolbachia-induced cytoplasmic incompatibility (C..