TREMOR AND COGNITION IN MULTIPLE SCLEROSIS: IMPLEMENTING NOVEL TREATMENTS AND COMPUTERIZED MONITORING STRATEGIES.
Grant number: 1123330 | Funding period: 2017 - 2018
This research program aims to study two disabling symptoms of multiple sclerosis namely upper limb shaking, or tremor, and memory dysfunction. The first project will develop a new treatment for MS arm tremor, Botulinum toxin injections, into routine clinical practice. The second project aims to make available a computerised test of memory that can be done in clinic waiting rooms or at home. This will help neurologists to rapidly pick up changes in memory in a person with MS and improve care.
Related publications (3)
The feasibility, reliability and concurrent validity of the MSReactor computerized cognitive screening tool in multiple sclerosis
Daniel Merlo, David Darby, Tomas Kalincik, Helmut Butzkueven, Anneke van der Walt
Background: Multiple sclerosis (MS) cognitive tests are resource intensive and limited by practice effects that prevent frequent r..
Validation of a precision tremor measurement system for multiple sclerosis
Thushara Perera, Wee-Lih Lee, Shivanthan AC Yohanandan, Nguyen Ai-Lan, Belinda Cruse, Frederique MC Boonstra, Gustavo Noffs, Adam P Vogel, Scott C Kolbe, Helmut Butzkueven, Andrew Evans, Anneke van der Walt
BACKGROUND: Tremor is a debilitating symptom of Multiple Sclerosis (MS). Little is known about its pathophysiology and treatments ..
Novel Functional MRI Task for Studying the Neural Correlates of Upper Limb Tremor
Frederique MC Boonstra, Thushara Perera, Gustavo Noffs, Cassandra Marotta, Adam P Vogel, Andrew H Evans, Helmut Butzkueven, Bradford A Moffat, Anneke van der Walt, Scott C Kolbe
Introduction: Tremor of the upper limbs is a disabling symptom that is present during several neurological disorders and is curren..