NATIONAL CENTRE FOR INFECTIONS IN CANCER (NCIC)
Grant number: 1116876 | Funding period: 2016 - 2022
This Centre of Research Excellence will translate the best available evidence to improve cancer outcomes through better management of infections in cancer patients, a rapidly growing group. We will establish new research networks to detect emerging multi resistant infections, develop guidelines on how to manage them, implement locally successful programs that have been shown to save lives nationally and validate new practice changing immune, bioinformatics and diagnostic technologies.
Related publications (32)
Dynamics of Epstein-Barr virus on post-transplant lymphoproliferative disorders after antithymocyte globulin-conditioned allogeneic hematopoietic cell transplant
Julian Lindsay, Jad Othman, Michelle K Yong, David Ritchie, Lynette Chee, KimHeng Tay, Shio Yen Tio, Ian Kerridge, Keith Fay, William Stevenson, Chris Arthur, Sharon C-A Chen, David CM Kong, Matthew Greenwood, Steven A Pergam, Catherine Liu, Monica A Slavin
BACKGROUND: The use of antithymocyte globulin (ATG) in allogeneic hematopoietic cell transplant (HCT) is associated with an increa..
Infection-Related Mortality in Adults and Children Undergoing Allogeneic Hematopoietic Cell Transplantation: An Australian Registry Report
Julian Lindsay, Ian Kerridge, Leonie Wilcox, Steven Tran, Tracey A O'Brien, Matthew Greenwood, Sharon C-A Chen, David CM Kong, Steven A Pergam, Catherine Liu, Monica A Slavin
Infection-related mortality (IRM) is the most common non-relapse-related cause of death reported after allogeneic hematopoietic ce..
The Role of In Vivo and Ex Vivo Diagnostic Tools in Severe Delayed Immune-Mediated Adverse Antibiotic Drug Reactions
Ana Copaescu, Effie Mouhtouris, Sara Vogrin, Fiona James, Kyra YL Chua, Natasha E Holmes, Abby Douglas, Monica A Slavin, Heather Cleland, Celia Zubrinich, Ar Kar Aung, Michelle SY Goh, Elizabeth J Phillips, Jason A Trubiano
BACKGROUND: The use of in vivo and ex vivo diagnostic tools for delayed immune-mediated adverse drug reactions is currently ill de..
The impact of pharmacist-led antifungal stewardship interventions in the hospital setting: a systematic review
Anna Khanina, Kelly A Cairns, David CM Kong, Karin A Thursky, Monica A Slavin, Jason A Roberts
Aim: To summarise the evidence on pharmacist-led antifungal stewardship (AFS) programs in the hospital setting and to evaluate the..
Excess cost of care associated with sepsis in cancer patients: Results from a population-based case-control matched cohort
Michelle Tew, Kim Dalziel, Karin Thursky, Murray Krahn, Lusine Abrahamyan, Andrew M Morris, Philip Clarke
BACKGROUND: Cancer patients are at significant risk of developing sepsis due to underlying malignancy and necessary treatments. Li..
National cost savings from an ambulatory program for low-risk febrile neutropenia patients in Australia
Michelle Tew, Daniel Forster, Benjamin W Teh, Kim Dalziel
Objective The management of low-risk febrile neutropenia (FN) patients through ambulatory programs has demonstrated comparative sa..
The Safety and Efficacy of an Oral Penicillin Challenge Program in Cancer Patients: A Multicenter Pilot Study
Jason A Trubiano, Olivia Smibert, Abby Douglas, Misha Devchand, Belinda Lambros, Natasha E Holmes, Kyra Y Chua, Elizabeth J Phillips, Monica A Slavin
Antibiotic allergies are reported by up to 1 in 4 cancer patients, almost 50% of which are considered low risk and precede the can..
Infections in patients with chronic lymphocytic leukaemia: Mitigating risk in the era of targeted therapies
Benjamin W Teh, Constantine S Tam, Sasanka Handunnetti, Leon J Worth, Monica A Slavin
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia with infections a leading cause of morbidity and mortality. Recen..
Implementation of a whole of hospital sepsis clinical pathway in a cancer hospital: impact on sepsis management, outcomes and costs.
Karin Thursky, Senthil Lingaratnam, Jasveer Jayarajan, Gabrielle M Haeusler, Benjamin Teh, Michelle Tew, Georgina Venn, Alison Hiong, Christine Brown, Vivian Leung, Leon J Worth, Kim Dalziel, Monica A Slavin
Infection and sepsis are common problems in cancer management affecting up to 45% of patients and are associated with significant ..
What, where and why: exploring fluorodeoxyglucose-PET's ability to localise and differentiate infection from cancer
Abby Douglas, Eddie Lau, Karin Thursky, Monica Slavin
PURPOSE OF REVIEW: To review the utility of FDG-PET imaging in detecting the cause of fever and infection in patients with cancer...
Patient-reported outcomes in cancer survivors: a population-wide cross-sectional study
Michael Jefford, Andrew C Ward, Karolina Lisy, Karen Lacey, Jon D Emery, Adam W Glaser, Hannah Cross, Mei Krishnasamy, Sue-Anne McLachlan, Jim Bishop
PURPOSE: There is a lack of robust population-based data regarding the lived experience of cancer survivors. This study assessed t..
Development and evaluation of an online educational resource about cancer survivorship for cancer nurses: a mixed-methods sequential study
T Shaw, P Yates, B Moore, K Ash, L Nolte, M Krishnasamy, J Nicholson, M Rynderman, J Avery, M Jefford
Cancer survivorship is recognised globally as a key issue. In spite of the key role played by nurses in survivorship care, there i..
A qualitative study of the post-treatment experiences and support needs of survivors of lymphoma
Leanne Monterosso, Karen Taylor, Violet Platt, Elizabeth Lobb, Meinir Krishnasamy, Toni Musiello, Caroline Bulsara, Kendall Stratton, David Joske
PURPOSE: To explore the post-treatment experiences and preferences for follow-up support of lymphoma survivors. METHODS: Two focus..
Barriers and facilitators to the implementation of audio-recordings and question prompt lists in cancer care consultations: A qualitative study
Natasha Moloczij, Mei Krishnasamy, Phyllis Butow, Thomas F Hack, Lesley Stafford, Michael Jefford, Penelope Schofield
OBJECTIVE: Question prompt lists (QPLs) and consultation audio-recordings (CARs) are two communication strategies that can assist ..
Self-guided interventions for managing psychological distress in people with cancer - A systematic review
Anna Ugalde, Kerry Haynes, Anna Boltong, Victoria White, Meinir Krishnasamy, Penelope Schofield, Sanchia Aranda, Patricia Livingston
OBJECTIVE: People with cancer can experience psychological distress but do not always desire, or engage with, professional support..
Individualised mindfulness-based stress reduction for head and neck cancer patients undergoing radiotherapy of curative intent: a descriptive pilot study
A Pollard, JL Burchell, D Castle, K Neilson, M Ftanou, J Corry, D Rischin, DW Kissane, M Krishnasamy, LE Carlson, J Couper
People with head and neck cancer (HNC) experience elevated symptom toxicity and co-morbidity as a result of treatment, which is as..
The Women's wellness after cancer program: a multisite, single-blinded, randomised controlled trial protocol
Debra Anderson, Charrlotte Seib, Dian Tjondronegoro, Jane Turner, Leanne Monterosso, Amanda McGuire, Janine Porter-Steele, Wei Song, Patsy Yates, Neil King, Leonie Young, Kate White, Kathryn Lee, Sonj Hall, Mei Krishnasamy, Kathy Wells, Sarah Balaam, Alexandra L McCarthy
BACKGROUND: Despite advances in cancer diagnosis and treatment have significantly improved survival rates, patients post-treatment..
The Cancer Nurse Coordinator Service in Western Australia: perspectives of specialist cancer nurse coordinators
Leanne Monterosso, Patsy Yates, Violet Platt, Caroline Bulsara, Meinir Krishnasamy
Objective In Western Australia the cancer nurse coordinator (CNC) role is unique, state wide and situated in nursing. It requires ..
Developing and evaluating Robocare; an innovative, nurse-led robotic prostatectomy care pathway
Emma Birch, Siska van Bruwaene, Wouter Everaerts, Kathryn Schubach, Matiu Bush, Mei Krishnasamy, Daniel A Moon, Jeremy Goad, Nathan Lawrentschuk, Declan G Murphy
PURPOSE: A Robotic Prostatectomy Care Pathway ("Robocare"), aiming to prepare men for robotic-assisted radical prostatectomy (RARP..
Developing an Evidence-Based, Nurse-Led Psychoeducational Intervention With Peer Support in Gynecologic Oncology
Rebecca J Bergin, Suzi M Grogan, David Bernshaw, Ilona Juraskova, Sylvia Penberthy, Linda R Mileshkin, Meinir Krishnasamy, Alison C Hocking, Sanchia K Aranda, Penelope E Schofield
BACKGROUND: The physical and psychosocial impact of radiotherapy for gynecologic cancer requires complex interventions to address ..
Early and Intensive Dietary Counseling in Lung Cancer Patients Receiving (Chemo)Radiotherapy-A Pilot Randomized Controlled Trial
Nicole Kiss, Elisabeth Isenring, Karla Gough, Greg Wheeler, Andrew Wirth, Belinda A Campbell, Meinir Krishnasamy
Malnutrition is prevalent in patients undergoing (chemo)radiotherapy (RT) for lung cancer. This pilot study tested the feasibility..
Psychological distress, quality of life, symptoms and unmet needs of colorectal cancer survivors near the end of treatment
Lahiru Russell, Karla Gough, Allison Drosdowsky, Penelope Schofield, Sanchia Aranda, Phyllis N Butow, Jennifer A Westwood, Mei Krishnasamy, Jane M Young, Jo Phipps-Nelson, Dorothy King, Michael Jefford
PURPOSE: This study investigated psychological morbidity, quality of life (QoL), colorectal cancer (CRC)-specific symptoms and sup..
A mixed method feasibility study of a patient- and family-centred advance care planning intervention for cancer patients
N Michael, C O'Callaghan, A Baird, K Gough, M Krishnasamy, N Hiscock, J Clayton
Background Advance care planning (ACP) is a process whereby values and goals are sensitively explored and documented to uphold pat..
Cancer care coordination: building a platform for the development of care coordinator roles and ongoing evaluation
Louise Freijser, Lucio Naccarella, Rosemary McKenzie, Meinir Krishnasamy
Continuity of care is integral to the quality and safety of care provided to people with cancer and their carers. Further evidence..
Supportive Care in Lung Cancer Milestones Over the Past 40 Years
Alex Molassiotis, Wilma Uyterlinde, Patricia J Hollen, Linda Sarna, Patricia Palmer, Meinir Krishnasamy
The evolution of supportive care in lung cancer (LC) is the focus of this article, which aims to present an overall picture of the..
Dosimetric factors associated with weight loss during (chemo)radiotherapy treatment for lung cancer
N Kiss, M Krishnasamy, S Everitt, K Gough, M Duffy, E Isenring
Background/Objectives:Thoracic radiotherapy (RT) is associated with acute toxicities, including oesophagitis, which can have an im..
The prevalence of weight loss during (chemo)radiotherapy treatment for lung cancer and associated patient- and treatment-related factors
Nicole Kiss, Elisabeth Isenring, Karla Gough, Meinir Krishnasamy
BACKGROUND & AIMS: Thoracic radiotherapy is associated with toxicities that can adversely impact nutritional intake. This study ai..
The Relationship between Self-Efficacy and Anxiety and General Distress in Caregivers of People with Advanced Cancer
Anna Ugalde, Meinir Krishnasamy, Penelope Schofield
BACKGROUND: Informal caregivers take on an important role in supporting people with advanced cancer but experience significant psy..