IMPROVING OUTCOMES IN SYSTEMIC AUTOIMMUNE DISEASE: A COLLABORATIVE AND INTERDISCIPLINARY PROGRAM OF RESEARCH
Grant number: 1126370 | Funding period: 2017 - 2020
The multi-organ autoimmune diseases ‘scleroderma’ and ‘lupus’ have a profound negative impact on quality of life and life expectancy. The overall goal of my research is to improve patient outcomes in these two diseases. My collaborative and interdisciplinary research program entails quantifying disease burden, identifying patient subsets, optimising screening for complications, developing outcome measures for use in practice and research, and trialing new therapies.
Related publications (39)
Development and validation of the Scleroderma Clinical Trials Consortium Damage Index (SCTC-DI): a novel instrument to quantify organ damage in systemic sclerosis
Nava Ferdowsi, Molla Huq, Wendy Stevens, Marie Hudson, Mianbo Wang, Tien Tay, Jodie L Burchell, Sam Mancuso, Candice Rabusa, Vijaya Sundararajan, David Prior, Susanna M Proudman, Murray Baron, Mandana Nikpour, Tracy Frech, Marie Hudson, Susanna Proudman, Wendy Stevens, Tien Tay, Souyma Chatterjee
Generation of a Core Set of Items to Develop Classification Criteria for Scleroderma Renal Crisis Using Consensus Methodology
Emily-Ann Butler, Murray Baron, Agnes B Fogo, Tracy Frech, Cybele Ghossein, Eric Hachulla, Sabrina Hoa, Sindhu R Johnson, Dinesh Khanna, Luc Mouthon, Mandana Nikpour, Susanna Proudman, Virginia Steen, Edward Stern, John Varga, Christopher Denton, Marie Hudson, April Barnado, Murray Baron, Elana J Bernstein
Severe gastrointestinal disease in very early systemic sclerosis is associated with early mortality
Nicolas Richard, Marie Hudson, Mianbo Wang, Genevieve Gyger, Susanna Proudman, Wendy Stevens, Mandana Nikpour, J Pope, M Larche, N Khalidi, A Masetto, E Sutton, D Robinson, TS Rodriguez-Reyna, D Smith, C Thorne, PR Fortin, M Fritzler, L Croyle, J de Jager
Development of the Asia Pacific Lupus Collaboration cohort
Rangi Kandane-Rathnayake, Vera Golder, Worawit Louthrenoo, Shue-Fen Luo, Yeong-Jian Jan Wu, Zhanguo Li, Yuan An, Aisha Lateef, Sargunan Sockalingam, Sandra V Navarra, Leonid Zamora, Laniyati Hamijoyo, Yasuhiro Katsumata, Masayoshi Harigai, Madelynn Chan, Sean O'Neill, Fiona Goldblatt, Yanjie Hao, Zhuoli Zhang, Jamal Al-Saleh
An interim report of the scleroderma clinical trials consortium working groups
M Baron, B Kahaleh, EJ Bernstein, L Chung, PJ Clements, C Denton, RT Domsic, N Ferdowsi, I Foeldvari, T Frech, JK Gordon, M Hudson, SR Johnson, D Khanna, Z McMahan, PA Merkel, S Narain, M Nikpour, JD Pauling, L Ross
Cost savings with a novel algorithm for early detection of systemic sclerosis-related pulmonary arterial hypertension.
Alannah QUINLIVAN, Susanna Proudman, Joanne Sahhar, Wendy Stevens, Mandana Nikpour, null on behalf of the Australian Scleroderma Interest Group (ASIG)
Pulmonary Arterial Hypertension (PAH) is an important cause of death and disability in Scleroderma (SSc) patients. Yearly screenin..
Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC vascular working group report
John D Pauling, Tracy M Frech, Michael Hughes, Jessica K Gordon, Robyn T Domsic, Marina E Anderson, Francesca Ingegnoli, Neil J McHugh, Sindhu R Johnson, Marie Hudson, Francesco Boini, Voon H Ong, Marco Matucci-Cerinic, Nezam Altorok, Marina Scolnik, Mandana Nikpour, Ankoor Shah, Janet E Pope, Dinesh Khanna, Ariane L Herrick
Determinants of health-related quality of life in a multinational systemic sclerosis inception cohort.
Kathleen Morrisroe, Marie Hudson, Murray Baron, Jeska de Vries-Bouwstra, Patricia E Carreira, Dirk M Wuttge, Mianbo Wang, Tracy M Frech, Wendy Stevens, Susanna M Proudman, Mandana Nikpour, null International Systemic Sclerosis Inception Cohort (INSYNC) collaboration
OBJECTIVES: To evaluate health-related quality of life (HRQoL) and its determinants in a systemic sclerosis (SSc) multinational in..
The role of inflammatory markers in assessment of disease activity in systemic sclerosis.
Laura Ross, Wendy Stevens, Candice Rabusa, Michelle Wilson, Nava Ferdowsi, Jennifer Walker, Joanne Sahhar, Gene-Siew Ngian, Jane Zochling, Janet Roddy, Kathleen Tymms, Gabor Major, Gemma Strickland, Susanna M Proudman, Mandana Nikpour
OBJECTIVES: The role of the erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in the assessment of disease activit..
CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages
Anushka N Samudra, Karen M Dwyer, Carly Selan, Susanna Freddi, Lisa Murray-Segal, Mandana Nikpour, Michael J Hickey, Karlheinz Peter, Simon C Robson, Maithili Sashindranath, Peter J Cowan, Harshal H Nandurkar
EVOLVE: The Australian Rheumatology Association's "top five' list of investigations and interventions doctors and patients should question
Kathleen Morrisroe, Ayano Nakayama, Jason Soon, Mark Arnold, Les Barnsley, Claire Barrett, Peter M Brooks, Stephen Hall, Patrick Hanrahan, Pravin Hissaria, Graeme Jones, Veera S Katikireddi, Helen Keen, Rodger Laurent, Mandana Nikpour, Katherine Poulsen, Philip Robinson, Muriel Soden, Nigel Wood, Nicola Cook
What have multicentre registries across the world taught us about the disease features of systemic sclerosis?
Susanna M Proudman, Molla Huq, Wendy Stevens, Michelle E Wilson, Joanne Sahhar, Murray Baron, Marie Hudson, Janet Pope, Yannick Allanore, Oliver Distler, Otylia Kowal-Bielecka, Marco Matucci-Cerinic, Andrea HL Low, Gim Gee Teng, Weng Giap Law, Amelia Santosa, Mandana Nikpour
Antifibrillarin Antibodies Are Associated with Native North American Ethnicity and Poorer Survival in Systemic Sclerosis
Carolina Mejia Otero, Shervin Assassi, Marie Hudson, Maureen D Mayes, Rosa Estrada-Y-Martin, Claudia Pedroza, Tingting W Mills, Jennifer Walker, Murray Baron, Wendy Stevens, Susanna M Proudman, Mandana Nikpour, Sonal Mehra, Mianbo Wang, Marvin J Fritzler
Does expert opinion match the operational definition of the Lupus Low Disease Activity State (LLDAS)? A case-based construct validity study
Vera Golder, Molla Huq, Kate Franklyn, Alicia Calderone, Aisha Lateef, Chak Sing Lau, Alfred Lok Hang Lee, Sandra Teresa V Navarra, Timothy Godfrey, Shereen Oon, Alberta Yik Bun Hoi, Eric Francis Morand, Mandana Nikpour
Long-term efficacy and tolerability of mycophenolate mofetil therapy in diffuse scleroderma skin disease
Daniel Boulos, Gene-Siew Ngian, Anton Rajadurai, Kathleen Elford, Wendy Stevens, Susanna Proudman, Claire Owen, Janet Roddy, Mandana Nikpour, Peter Youssef, Catherine Hill, Joanne Sahhar
Association of the lupus low disease activity state (LLDAS) with health-related quality of life in a multinational prospective study
Vera Golder, Rangi Kandane-Rathnayake, Alberta Yik-Bun Hoi, Molla Huq, Worawit Louthrenoo, Yuan An, Zhan Guo Li, Shue Fen Luo, Sargunan Sockalingam, Chak Sing Lau, Mo Yin Mok, Aisha Lateef, Kate Franklyn, Susan Morton, Sandra Teresa V Navarra, Leonid Zamora, Yeong-Jian Wu, Laniyati Hamijoyo, Madelynn Chan, Sean O'Neill