Toward An Evidence-Based Approach For Treating End-Stage Knee Arthritis
Grant number: 1122526 | Funding period: 2017 - 2020
World-wide more than one million total knee replacements (TKR) will be performed for end-stage knee osteoarthritis in 2016 alone. With an ageing population, demand for this procedure will increase dramatically, placing burden on a constrained health system. Up to 25% of TKR recipients experience on going pain after surgery and are dissatisfied with TKR. My research seeks to improve efficiencies and equitability of this important surgical procedure and in doing so optimise patient outcomes
Related publications (41)
A blinded, three-arm randomised trial assessing joint function and measuring three-dimensional knee joint kinematics in individuals six months after a total knee joint replacement; comparing a medially stabilised design, to standard fixed bearing conventional designs – posterior stabilising and cruciate retaining
Michelle M Dowsey, Marcus Pandy, Tony J Young, Hans Gray, Shangyuanye Guan, Peter F Choong
<jats:p><p class="abstract"><strong>Background:</strong> No randomised trial exists to assess the relative prost..
What Influences Patient Satisfaction after TKA? A Qualitative Investigation.
Nardia-Rose Klem, Anne Smith, Peter O'Sullivan, Michelle M Dowsey, Robert Schütze, Peter Kent, Peter F Choong, Samantha Bunzli
BACKGROUND: Patient satisfaction is a common measure of the success of an orthopaedic intervention. However, there is poor underst..
Risk Factors for Chronic Opioid Use Following Hip and Knee Arthroplasty: Evidence from New Zealand Population Data.
Yana Pryymachenko, Ross A Wilson, J Haxby Abbott, Michelle M Dowsey, Peter FM Choong
BACKGROUND: Patients awaiting total joint arthroplasty (TJA) have high rates of opioid use, and many continue to use opioid medica..
A Randomized Controlled Trial Comparing a Medial Stabilised Total Knee Prosthesis to a Cruciate Retaining and Posterior Stabilised Design - A Report of the Clinical and Functional Outcomes Following Total Knee Replacement
Michelle M Dowsey, Daniel Gould, Tim Spelman, Marcus G Pandy, Peter F Choong
Background The purpose of this randomized controlled trial was to compare the performance of 3 total knee joint replacement (TKJR)..
Misconceived expectations: Patient reflections on the total knee replacement journey
Samantha Bunzli, Penny O'Brien, Nardia Klem, Ian Incoll, Jasvinder Singh, Myles Davaris, Peter Choong, Michelle Dowsey
INTRODUCTION: Fifty per cent of patients consent for total knee replacement (TKR) with unrealistic expectations about what it invo..
Exploring the Impact of Quality of Life on Survival: A Case Study in Total Knee Replacement Surgery
Michelle Tew, Kim Dalziel, Michelle Dowsey, Peter F Choong, Philip Clarke
Background. There is growing evidence that quality of life (QoL) has a strong association with mortality. However, incorporation o..
In pursuit of enhanced recovery after total joint replacement: a narrative review of drivers of length of stay
Siddharth Rele, Michelle M Dowsey, Peter FM Choong
A continual increase in the prevalence of osteoarthritis drives growing demand for total joint arthroplasty. So far, a decrease in..
Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment
Laura Wall, Madeleine Hinwood, Danielle Lang, Angela Smith, Samantha Bunzli, Philip Clarke, Peter FM Choong, Michelle M Dowsey, Francesco Paolucci
INTRODUCTION: In order to properly evaluate the efficacy of orthopaedic procedures, rigorous, randomised controlled sham surgery t..
Satisfaction after total knee replacement for osteoarthritis is usually high, but what are we measuring? A systematic review
Nardia-Rose Klem, Peter Kent, Anne Smith, Michelle Dowsey, Robyn Fary, Rob Schütze, Peter O'Sullivan, Peter Choong, Samantha Bunzli
Objective: Patient satisfaction is considered an important outcome measure after total knee replacement, but the construct is comp..
The influence of sex and pre-operative obesity on biomechanics two years after total knee arthroplasty: A longitudinal cohort study
KL Paterson, L Sosdian, KL Bennell, BR Metcalf, T Wrigley, J Kasza, MM Dowsey, PF Choong, RS Hinman
BACKGROUND: Sex and obesity may influence knee biomechanics associated with poor outcomes following primary total knee arthroplast..
Patient-related risk factors for unplanned 30-day readmission following total knee arthroplasty: a narrative literature review
Daniel Gould, Michelle Dowsey, Imkyeong Jo, Peter Choong
Osteoarthritis is a debilitating condition as well as a growing global health problem, and total knee arthroplasty (TKA) is an eff..
Co-Morbidities and Sex Differences in Long-Term Quality-of-Life Outcomes among Patients with and without Diabetes after Total Knee Replacement: Five-Year Data from Registry Study
Michelle Tew, Michelle M Dowsey, Annabelle Choong, Peter F Choong, Philip Clarke
Improved understanding of quality-of-life (QoL) outcomes can provide valuable information on intervention effectiveness and guide ..
The Surgeon's Role in the Opioid Crisis: A Narrative Review and Call to Action
Cade Shadbolt, J Haxby Abbott, Ximena Camacho, Philip Clarke, L Stefan Lohmander, Tim Spelman, Eric C Sun, Jonas B Thorlund, Yuting Zhang, Michelle M Dowsey, Peter FM Choong
Over the past two decades, there has been a sharp rise in the use of prescription opioids. In several countries, most notably the ..
Opioid use prior to elective surgery is strongly associated with persistent use following surgery: an analysis of 14 354 Medicare patients
Max Catchpool, Josh Knight, Jesse T Young, Philip Clarke, Michael J Barrington, Peter FM Choong, Michelle M Dowsey
BACKGROUND: Persistent opioid use following total joint replacement (TJR) surgery is common; however, the association between pre-..
Chlorhexidine-alcohol versus iodineealcohol for surgical site skin preparation in an elective arthroplasty (ACAISA) study: a cluster randomized controlled trial
TN Peel, MM Dowsey, KL Buising, AC Cheng, PFM Choong
OBJECTIVES: Surgical site skin preparation is an effective method to prevent wound complications. The optimal agent has not been e..
The effect of mindfulness training prior to total joint arthroplasty on postoperative pain and physical function: A randomised controlled trial
Michelle Dowsey, David Castle, Simon Knowles, Kaveh Monshat, Michael Salzberg, Elizabeth Nelson, Anthony Dunin, Jo Dunin, Tim Spelman, Peter Choong
Misconceptions and the Acceptance of Evidence-based Nonsurgical Interventions for Knee Osteoarthritis. A Qualitative Study
Samantha Bunzli, Penny O'Brien, Darshini Ayton, Michelle Dowsey, Jane Gunn, Peter Choong, Jo-Anne Manski-Nankervis
BACKGROUND: In contrast to best practice guidelines for knee osteoarthritis (OA), findings from several different healthcare setti..
What are the patient factors that impact on decisions to progress to total knee replacement? A qualitative study involving patients with knee osteoarthritis
Penny O'Brien, Samantha Bunzli, Darshini Ayton, Michelle M Dowsey, Jane Gunn, Jo-Anne Manski-Nankervis
OBJECTIVES: General practitioners (GPs) are often the first health professionals to assess patients with osteoarthritis (OA). Desp..
How do surgeons' trade-off between patient outcomes and risk of complications in total knee arthroplasty? a discrete choice experiment in Australia
Sandie Szawlowski, Peter FM Choong, Jinhu Li, Elizabeth Nelson, Mandana Nikpour, Anthony Scott, Vijaya Sundararajan, Michelle M Dowsey
OBJECTIVE: To measure the trade-off between risk of complications versus patient improvement in pain and function in orthopaedic s..
Achieving Consensus on Total Joint Replacement Trial Outcome Reporting Using the OMERACT Filter: Endorsement of the Final Core Domain Set for Total Hip and Total Knee Replacement Trials for Endstage Arthritis
Jasvinder A Singh, Michelle M Dowsey, Michael Dohm, Susan M Goodman, Amye L Leong, Marieke MJH Scholte Voshaar, Peter F Choong
Barriers and facilitators to orthopaedic surgeons’ uptake of decision aids for total knee arthroplasty: a qualitative study
A Scott, S Bunzli, S French, P Choong, M Dowsey
Objectives: The demand for total knee arthroplasty (TKA) is increasing. Differentiating who will derive a clinically meaningful im..