MAIT CELLS IN BACTERIAL INFECTION. FRIEND OR FOE?

Grant number: 1120467 | Funding period: 2017 - 2019

Completed

Abstract

A specialised set of T lymphocytes called Mucosal Associated Invariant T (MAIT) cells react against bacteria and yeast, and reside at mucosal sites where the body's immune defences are most easily breached, e.g. respiratory tract and intestinal mucosa. This study investigates the role of MAIT cells in both protection and pathology in bacterial infections. Controlling MAIT cells could help in treating these conditions.

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