SYTEMIC AND MUCOSAL FUNCTIONAL ANTIBODIES IN PROTECTION AGAINST HIV
Grant number: 1125164 | Funding period: 2017 - 2019
Only one human HIV vaccine has shown any level of protective efficacy. However the mechanisms behind how this vaccine was protective are still not fully understood. Additionally, HIV is primarily transmitted through mucosal sites, however very little is know about vaccine immune responses at these sites. Thus this proposal aims to further define the mechanisms of antibody protection against HIV at both systemic and mucosal locations, in order to guide future HIV vaccine design efforts.
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