CHARACTERIZATION OF THE TYPE IX SECRETION SYSTEM IN PORPHYROMONAS GINGIVALIS

Grant number: 1123866 | Funding period: 2017 - 2020

Completed

Abstract

Periodontitis is associated with the keystone pathogen Porphyromonas gingivalis. We have identified a novel protein secretion machine comprised of at least 12 components in P. gingivalis which transports the bacterium's major virulence factors to the cell surface and attaches them to the outer membrane. We aim to determine the spatial arrangement and specific role of each of these 12 components and thereby provide targets for future treatments against this disease.

Related publications (6)

University of Melbourne Researchers