MECHANISMS OF REGULATING GENE EXPRESSION VIA SELECTIVE MRNA TRANSPORT

RNA in cancer

Gregory J Goodall, Vihandha O Wickramasinghe

2020-10-20

While the processing of mRNA is essential for gene expression, recent findings have highlighted that RNA processing is systematica..

Regulatory Potential of the RNA Processing Machinery: Implications for Human Disease

Kirstyn T Carey, Vihandha O Wickramasinghe

2018-04-01

Splicing and nuclear export of mRNA are critical steps in the gene expression pathway. While RNA processing factors can perform ge..

Nuclear export of RNA: Different sizes, shapes and functions

Tobias Williams, Linh H Ngo, Vihandha O Wickramasinghe

2018-03-01

Export of protein-coding and non-coding RNA molecules from the nucleus to the cytoplasm is critical for gene expression. This nece..

Impact of Alternative Splicing on the Human Proteome

Yansheng Liu, Mar Gonzalez-Porta, Sergio Santos, Alvis Brazma, John C Marioni, Ruedi Aebersold, Ashok R Venkitaraman, Vihandha O Wickramasinghe

2017-08-01

Alternative splicing is a critical determinant of genome complexity and, by implication, is assumed to engender proteomic diversit..