INTEROGATION OF THE GENOMIC EPIDEMIOLOGY AND NEPHRITOGENICITY WITHIN INDIGENOUS REGIONS ENDEMIC FOR GROUP A STREPTOCOCCAL DISEASE
Grant number: 1130455 | Funding period: 2017 - 2020
Group A streptococcal (GAS) bacterial infections within the Indigenous populations of Northern Australia are amongst the highest in the world. This project uses comparative bacterial genomics to examine current and historical outbreaks of GAS disease in Northern Australia relative to globally sourced GAS. This will be used to examine the spread of disease causing GAS between remote communities as well as investigating genetic markers of disease and informing therapeutic interventions.
Related publications (6)
Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection
Rebecca H Chisholm, Nikki Sonenberg, Jake A Lacey, Malcolm I McDonald, Manisha Pandey, Mark R Davies, Steven YC Tong, Jodie McVernon, Nicholas Geard
Group A Streptococcus (GAS) skin infections are caused by a diverse array of strain types and are highly prevalent in disadvantage..
Biphasic Outbreak of Invasive Group A Streptococcus Disease in Eldercare Facility, New Zealand
Kate A Worthing, Anja Werno, Ramon Pink, Liam McIntyre, Glen P Carter, Deborah A Williamson, Mark R Davies
A 3-month outbreak of invasive group A Streptococcus disease at an eldercare facility, in which 5 persons died, was biphasic. Alth..
Longitudinal Analysis of Group A Streptococcus emm Types and emm Clusters in a High-Prevalence Setting: Relationship between Past and Future Infections.
Patricia Therese Campbell, Steven YC Tong, Nicholas Geard, Mark R Davies, Kate A Worthing, Jake A Lacey, Pierre R Smeesters, Michael R Batzloff, Joseph Kado, Adam WJ Jenney, Jodie Mcvernon, Andrew C Steer
Group A Streptococcus is a pathogen of global importance, but despite the ubiquity of group A Streptococcus infections, the relati..
Identification and Characterization of Fluoroquinolone Non-susceptible Streptococcus pyogenes Clones Harboring Tetracycline and Macrolide Resistance in Shanghai, China
Yinfang Shen, Jiehao Cai, Mark R Davies, Chi Zhang, Kun Gao, Dan Qiao, Haoqin Jiang, Weilei Yao, Yuefang Li, Mei Zeng, Mingliang Chen
Streptococcus pyogenes, also known as group A Streptococcus (GAS), is one of the top 10 infectious causes of death worldwide. Macr..