CHARACTERISATION OF ANTI-HBS RESPONSES IN PATIENTS UNDERGOING FUNCTIONAL HEPATITIS B CURE: IMPLICATION FOR FUTURE THERAPIES

Grant number: 1127538 | Funding period: 2017 - 2020

Completed

Abstract

The hepatitis B virus causes liver cirrhosis and liver cancer. There is no cure for hepatitis B. However, a small number of patients can naturally rid themselves of the virus. We have identified 14 of these individuals and discovered that they have a unique immune response that is responsible for these “natural” cures. We plan to characterise this immune response and turn it into a therapeutic vaccine which can be used to cure patients who are still chronically infected.