TOWARDS A FUNCTIONAL CURE FOR HBV: EXPLOITING LESSONS FROM HBV-HIV CO-INFECTION

Grant number: 1123988 | Funding period: 2017 - 2021

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Abstract

Hepatitis B virus (HBV) infection can be treated, but therapy is usually lifelong and has side effects, so a cure for HBV is very important. We work closely with colleagues in Asia where both HBV and HIV are common so this provides a unique opportunity to study HBV. We will investigate how an effective immune response against the 2 main HBV proteins is developed. If we can understand how the immune response works against HBV, this could be used to develop new therapies to develop a cure for HBV