Circulating Tumour Dna As A Personalized Biomarker In Er Positive Metastatic Breast Cancer

Grant number: 1134017 | Funding period: 2018 - 2021

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Abstract

This PhD aims to study the use of liquid biopsies for disease monitoring in metastatic estrogen receptor positive breast cancer. Liquid biopsies involve looking for circulating cancer-specific genetic material in the blood stream. Through the use of liquid biopsies, we hope to understand genetic differences and heterogeneity within metastatic breast cancer; identify potential therapeutic targets; and examine the mechanisms of treatment resistance to facilitate personalised cancer therapy.