Targeted Therapy In Genetic Epilepsy

Grant number: 1106035 | Funding period: 2016 - 2018

Completed

Abstract

The aim of this application is to find new therapeutic strategies for genetic epilepsy. "Disease in a dish" models as well as whole animal models will be generated that contain patient gene mutations and the underlying disease processes will be characterised. Using these models a range of existing and new drugs will be tested to select those that most completely reverse these disease processes. These results will feed into clinical trials in patients with appropriate genetic profiles.

Researchers