TARGETING BREAST CANCER USING ADOPTIVE CELL TRANSFER INCORPORATING VACCINATION
Grant number: CCR16376637 | Funding period: 2017 - 2020
Related publications (8)
A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer.
Aesha I Ali, Minyu Wang, Bianca von Scheidt, Pilar M Dominguez, Aaron J Harrison, Daniela Gm Tantalo, Jian Kang, Amanda J Oliver, Jack D Chan, Xin Du, Yuchen Bai, Belinda Lee, Ricky W Johnstone, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
PURPOSE: In this article, we describe a combination chimeric antigen receptor (CAR) T-cell therapy that eradicated the majority of..
Enhancing chimeric antigen receptor T-cell immunotherapy against cancer using a nanoemulsion-based vaccine targeting cross-presenting dendritic cells
Jack D Chan, Bianca von Scheidt, Bijun Zeng, Amanda J Oliver, Ashleigh S Davey, Aesha Ali, Ranjeny Thomas, Joseph A Trapani, Phillip K Darcy, Michael H Kershaw, Riccardo Dolcetti, Clare Y Slaney
Objectives: Adoptive transfer of chimeric antigen receptor (CAR)-modified T cells is a form of cancer immunotherapy that has achie..
Enterotoxins can support CAR T cells against solid tumors
Bianca von Scheidt, Minyu Wang, Amanda J Oliver, Jack D Chan, Metta K Jana, Aesha I Ali, Fiona Clow, John D Fraser, Kylie M Quinn, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
Responses of solid tumors to chimeric antigen receptor (CAR) T cell therapy are often minimal. This is potentially due to a lack o..
Genetic Redirection of T Cells for the Treatment of Pancreatic Cancer
Aesha I Ali, Amanda J Oliver, Tinaz Samiei, Jack D Chan, Michael H Kershaw, Clare Y Slaney
Conventional treatments for pancreatic cancer are largely ineffective, and the prognosis for the vast majority of patients is poor..
Tissue-specific tumor microenvironments influence responses to immunotherapies
Amanda J Oliver, Ashleigh S Davey, Simon P Keam, Sherly Mardiana, Jack D Chan, Bianca von Scheidt, Paul A Beavis, Imran G House, Jonas RM Van Audernaerde, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
Objectives: Investigation of variable response rates to cancer immunotherapies has exposed the immunosuppressive tumor microenviro..
An ultrastructural investigation of tumors undergoing regression mediated by immunotherapy
Jennifer A Westwood, Sarah Ellis, Jill Danne, Chad Johnson, Viola Oorschot, Georg Ramm, David C Tscharke, Alexander J Davenport, James C Whisstock, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney
While immunotherapy employing chimeric antigen receptor (CAR) T cells can be effective against a variety of tumor types, little is..