MOLECULAR STRUCTURE ELUCIDATION FACILITY

Grant number: LE170100065 | Funding period: 2017 - 2018

Completed

Abstract

This project aims to provide state-of-the-art X-ray diffraction instrumentation in a shared research facility. X-ray diffraction is essential for many research programmes, and the facility would support research in chemical synthesis, materials chemistry and structural biology. Structure determinations makes it possible to understand the underlying molecular structure of complex chemical and biological systems in terms of the underlying molecular structure. Anticipated outcomes are scientific and economic benefits to Australia arising from the training of young scientists and advancements in technology and medicine.

Related publications (11)

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Phytochemical Profiling and Biological Testing of the Constituents of the Australian Plant Haemodorum brevisepalum.

Edward Owen Norman, Stuart Hombsch, James Lever, Robert Brkljača, Jonathan White, Robin B Gasser, Aya C Taki, Sylvia Urban

2021-11-26

Phytochemical profiling was undertaken on the crude extracts of the bulbs, stems, and the fruits of Haemodorum brevisepalum, to de..

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Examination of N,N-dimethylbenzylamine as a substrate for ruthenium-catalysed C-H (thio)amidation: A mass spectrometry and DFT directed study

Weam AO Altalhi, Alasdair I McKay, Benjamin Spyrou, Allan J Canty, Paul S Donnelly, Richard AJ O'Hair

2021-10-01

Key steps in the potential application of N,N-dimethylbenzylamine, a widely used substrate in organometallic chemistry, in rutheni..

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Revealing the influence of steric bulk on the triplet-triplet annihilation upconversion performance of conjugated polymers

Riley O'shea, William J Kendrick, Can Gao, Tze Cin Owyong, Jonathan M White, Kenneth P Ghiggino, Wallace WH Wong

2021-10-01

A series of poly(phenylene-vinylene)-based copolymers are synthesized using the Gilch method incorporating monomers with stericall..

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Selective Synthesis of C-1-Symmetric BINOL-phosphates and P-chiral Phosphoramides Using Directed ortho-Lithiation

Rohan Volpe, Hanson Y-L Law, Jonathan M White, Bernard L Flynn

2021-09-17

Directed ortho-lithiation (DoL) has been developed as an effective method for the ortho-substitution of BINOL-phosphoric acid and ..

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Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna (vol 84, pg 964, 2021)

Edward Owen Norman, Hayden Tuohey, David Pizzi, Milane Saidah, Rachael Bell, Robert Brkljaca, Jonathan M White, Robin B Gasser, Aya C Taki, Sylvia Urban

2021-07-23

With respect to the structures of compounds10-12, an error was noted. The compounds were incorrectly presented as 2,3-dihydro-1,4-..

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Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna

Edward Owen Norman, Hayden Tuohey, David Pizzi, Milane Saidah, Rachael Bell, Robert Brkljaca, Jonathan M White, Robin B Gasser, Aya C Taki, Sylvia Urban

2021-04-23

Phytochemical profiling was undertaken on the crude extracts of Drosera magna to determine the nature of the chemical constituents..

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Oxidative damage of proline residues by nitrate radicals (NO3): a kinetic and product study

Joses G Nathanael, Jonathan M White, Annika Richter, Madison R Nuske, Uta Wille

2020-09-21

Tertiary amides, such as in N-acylated proline or N-methyl glycine residues, react rapidly with nitrate radicals (NO3˙) with absol..

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Oxidative Repair of Pyrimidine Cyclobutane Dimers by Nitrate Radicals (NO3 center dot): A Kinetic and Computational Study

Tomas Haddad, Joses G Nathanael, Jonathan M White, Uta Wille

2020-06-01

<jats:p>Pyrimidine cyclobutane dimers are hazardous DNA lesions formed upon exposure of DNA to UV light, which can be repaired thr..

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Experimental evidence of chalcogen bonding at oxygen

Thomas Fellowes, Benjamin L Harris, Jonathan M White

2020-03-18

An o-nitro-O-aryl oxime was observed to exhibit a short OO contact, which exhibited characteristics consistent with a chalcogen bo..

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Palladium-Mediated CO2 Extrusion Followed by Insertion of Isocyanates for the Synthesis of Benzamides: Translating Fundamental Mechanistic Studies To Develop a Catalytic Protocol

Yang Yang, Allan J Canty, Alasdair McKay, Paul S Donnelly, Richard AJ O'Hair

2020-02-10

Mechanistic studies of a stoichiometric palladium-mediated ExIn (ExIn = extrusion-insertion) decarboxylative amidation of aromatic..

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Structural characterization and gas-phase studies of the [Ag10H8(L)(6)](2 ) nanocluster dication

Howard Z Ma, Alasdair McKay, Antonia Mravak, Michael S Scholz, Jonathan M White, Roger J Mulder, Evan J Bieske, Vlasta Bonacic-Koutecky, Richard AJ O'Hair

2019-12-21

The reactions between silver salts and borohydrides produce a rich set of products that range from discrete mononuclear compounds ..