A HIGH-PERFORMANCE CLOUD RESOURCE FOR COMPUTATIONAL MODELLING
Grant number: LE170100200 | Funding period: 2017 - 2017
This project aims to build a relatively low-cost graphical-processing-unit-based cloud-accessible facility. Much current cutting-edge research is based on intensive computational models and simulations, which are used to deepen our understanding and predict real-world phenomena. This facility will provide a specialised computational platform for high-fidelity predictive models and simulations. It will underpin research in critical fields of science and engineering and be used by researchers from across Australia. This facility's computational capabilities are expected to complement other national computing resources, keep Australia globally competitive, and enhance research in fields includi..View full description
Related publications (20)
Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae
Marina L Zupan, Zhenyao Luo, Katherine Ganio, Victoria G Pederick, Stephanie L Neville, Evelyne Deplazes, Bostjan Kobe, Christopher A McDevitt
Streptococcus pneumoniae scavenges essential zinc ions from the host during colonization and infection. This is achieved by the AT..
The structural basis of bacterial manganese import
Stephanie L Neville, Jennie Sjoehamn, Jacinta A Watts, Hugo MacDermott-Opeskin, Stephen J Fairweather, Katherine Ganio, Alex Carey Hulyer, Aaron P McGrath, Andrew J Hayes, Tess R Malcolm, Mark R Davies, Norimichi Nomura, So Iwata, Megan L O'Mara, Megan J Maher, Christopher A McDevitt
Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary import p..
Fluorinated Metal-Organic Coatings with Selective Wettability
Shuaijun Pan, Joseph J Richardson, Andrew J Christofferson, Quinn A Besford, Tian Zheng, Barry J Wood, Xiaofei Duan, Maximiliano Jesus Jara Fornerod, Christopher F McConville, Irene Yarovsky, Stefan Guldin, Lei Jiang, Frank Caruso
Surface chemistry is a major factor that determines the wettability of materials, and devising broadly applicable coating strategi..
Using machine learning to examine associations between the built environment and physical function: A feasibility study
Jerome N Rachele, Jingcheng Wang, Jasper S Wijnands, Haifeng Zhao, Rebecca Bentley, Mark Stevenson
Linking geospatial neighbourhood design characteristics to health and behavioural data from population-representative cohorts is l..
Automating the assessment of biofouling in images using expert agreement as a gold standard
Nathaniel J Bloomfield, Susan Wei, Bartholomew A Woodham, Peter Wilkinson, Andrew P Robinson
Biofouling is the accumulation of organisms on surfaces immersed in water. It is of particular concern to the international shippi..
Identifying safe intersection design through unsupervised feature extraction from satellite imagery
Jasper S Wijnands, Haifeng Zhao, Kerry A Nice, Jason Thompson, Katherine Scully, Jingqiu Guo, Mark Stevenson
The World Health Organization has listed the design of safer intersections as a key intervention to reduce global road trauma. Thi..
BAK core dimers bind lipids and can be bridged by them
Angus D Cowan, Nicholas A Smith, Jarrod J Sandow, Eugene A Kapp, Yepy H Rustam, James M Murphy, Jason M Brouwer, Jonathan P Bernardini, Michael J Roy, Ahmad Z Wardak, Iris K Tan, Andrew I Webb, Jacqueline M Gulbis, Brian J Smith, Gavin E Reid, Grant Dewson, Peter M Colman, Peter E Czabotar
BAK and BAX are essential mediators of apoptosis that oligomerize in response to death cues, thereby causing permeabilization of t..
First record of a tandem-repeat region within the mitochondrial genome ofClonorchis sinensisusing a long-read sequencing approach
Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser
BACKGROUND: Mitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helmin..
A constricted opening in Kir channels does not impede potassium conduction
Katrina A Black, Sitong He, Ruitao Jin, David M Miller, Jani R Bolla, Oliver B Clarke, Paul Johnson, Monique Windley, Christopher J Burns, Adam P Hill, Derek Laver, Carol Robinson, Brian J Smith, Jacqueline M Gulbis
The canonical mechanistic model explaining potassium channel gating is of a conformational change that alternately dilates and con..
A structurally minimized yet fully active insulin based on cone-snail venom insulin principles
Xiaochun Xiong, John G Menting, Maria M Disotuar, Nicholas A Smith, Carlie A Delaine, Gabrielle Ghabash, Rahul Agrawal, Xiaomin Wang, Xiao He, Simon J Fisher, Christopher A MacRaild, Raymond S Norton, Joanna Gajewiak, Briony E Forbes, Brian J Smith, Helena Safavi-Hemami, Baldomero Olivera, Michael C Lawrence, Danny Hung-Chieh Chou
Human insulin and its current therapeutic analogs all show propensity, albeit varyingly, to self-associate into dimers and hexamer..
The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody
Caroline Soliman, Jia Xin Chua, Mireille Vankemmelbeke, Richard S McIntosh, Andrew J Guy, Ian Spendlove, Lindy G Durrant, Paul A Ramsland
Cancer remains a leading cause of morbidity and mortality worldwide, requiring ongoing development of targeted therapeutics such a..
Real-time monitoring of driver drowsiness on mobile platforms using 3D neural networks
Jasper S Wijnands, Jason Thompson, Kerry A Nice, Gideon DPA Aschwanden, Mark Stevenson
Driver drowsiness increases crash risk, leading to substantial road trauma each year. Drowsiness detection methods have received c..
Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains
Sofia Caria, Bryce Z Stewart, Ruitao Jin, Brian J Smith, Patrick O Humbert, Marc Kvansakul
Scribble is a crucial adaptor protein that plays a pivotal role during establishment and control of cell polarity, impacting many ..