DELIVERING ADVANCED ELECTRODE MATERIALS TO THE CLINIC

Grant number: 1122055 | Funding period: 2017 - 2020

Completed

Abstract

This research will develop improved electrodes for interfacing neural tissue by combining the expertise of materials scientists and electrophysiologists with medical bionics researchers. This work is expected to deliver improved bionic devices to the clinic in order to treat a variety of disorders from blindness to the control of motor tremor in Parkinson's disease.

Related publications (7)

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Rapid electrophoretic deposition of biocompatible graphene coatings for high-performance recording neural electrodes

Miheng Dong, Harold A Coleman, Mary A Tonta, Zhiyuan Xiong, Dan Li, Sebastian Thomas, Minsu Liu, James B Fallon, Helena C Parkington, John S Forsythe

2022-10-12

The electrical and biological interfacial properties of invasive electrodes have a significant impact on the performance and longe..

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Improving Deep Brain Stimulation Electrode Performance in vivo Through Use of Conductive Hydrogel Coatings.

Tomoko Hyakumura, Ulises Aregueta-Robles, Wenlu Duan, Joel Villalobos, Wendy K Adams, Laura Poole-Warren, James B Fallon

2021-01-05

Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement dis..

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Electrochemical and biological characterization of thin-film platinum-iridium alloy electrode coatings: a chronic in vivo study

Ashley N Dalrymple, Mario Huynh, Bryony A Nayagam, Curtis D Lee, Greg R Weiland, Artin Petrossians, J John, III Whalen, James B Fallon, Robert K Shepherd

2020-06-01

OBJECTIVE: To evaluate the electrochemical properties, biological response, and surface characterization of an electrodeposited Pl..

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Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes

Ashley N Dalrymple, Ulises A Robles, Mario Huynh, Bryony A Nayagam, Rylie A Green, Laura A Poole-Warren, James B Fallon, Robert K Shepherd

2020-04-01

OBJECTIVE: Evaluate electrochemical properties, biological response, and surface characterization of a conductive hydrogel (CH) co..

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Electrochemical and mechanical performance of reduced graphene oxide, conductive hydrogel, and electrodeposited Pt-Ir coated electrodes: an active in vitro study

Ashley N Dalrymple, Mario Huynh, Ulises Aregueta Robles, Jason B Marroquin, Curtis D Lee, Artin Petrossians, John J Whalen, Dan Li, Helena C Parkington, John S Forsythe, Rylie A Green, Laura A Poole-Warren, Robert K Shepherd, James B Fallon

2020-02-01

OBJECTIVE: To systematically compare the in vitro electrochemical and mechanical properties of several electrode coatings that hav..

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Neurotrophin gene augmentation by electrotransfer to improve cochlear implant hearing outcomes

Jeremy L Pinyon, Georg von Jonquieres, Edward N Crawford, Mayryl Duxbury, Amr Al Abed, Nigel H Lovell, Matthias Klugmann, Andrew K Wise, James B Fallon, Robert K Shepherd, Catherine S Birman, Waikong Lai, David McAlpine, Catherine McMahon, Paul M Carter, Ya Lang Enke, James F Patrick, Anne GM Schilder, Corinne Marie, Daniel Scherman

2019-09-01

This Review outlines the development of DNA-based therapeutics for treatment of hearing loss, and in particular, considers the pot..

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New molecular therapies for the treatment of hearing loss

Yutian Ma, Andrew K Wise, Robert K Shepherd, Rachael T Richardson

2019-08-01

An estimated 466 million people suffer from hearing loss worldwide. Sensorineural hearing loss is characterized by degeneration of..

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