DELIVERING ADVANCED ELECTRODE MATERIALS TO THE CLINIC
Grant number: 1122055 | Funding period: 2017 - 2020
This research will develop improved electrodes for interfacing neural tissue by combining the expertise of materials scientists and electrophysiologists with medical bionics researchers. This work is expected to deliver improved bionic devices to the clinic in order to treat a variety of disorders from blindness to the control of motor tremor in Parkinson's disease.
Related publications (7)
Rapid electrophoretic deposition of biocompatible graphene coatings for high-performance recording neural electrodes
Miheng Dong, Harold A Coleman, Mary A Tonta, Zhiyuan Xiong, Dan Li, Sebastian Thomas, Minsu Liu, James B Fallon, Helena C Parkington, John S Forsythe
The electrical and biological interfacial properties of invasive electrodes have a significant impact on the performance and longe..
Improving Deep Brain Stimulation Electrode Performance in vivo Through Use of Conductive Hydrogel Coatings.
Tomoko Hyakumura, Ulises Aregueta-Robles, Wenlu Duan, Joel Villalobos, Wendy K Adams, Laura Poole-Warren, James B Fallon
Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement dis..
Electrochemical and biological characterization of thin-film platinum-iridium alloy electrode coatings: a chronic in vivo study
Ashley N Dalrymple, Mario Huynh, Bryony A Nayagam, Curtis D Lee, Greg R Weiland, Artin Petrossians, J John, III Whalen, James B Fallon, Robert K Shepherd
OBJECTIVE: To evaluate the electrochemical properties, biological response, and surface characterization of an electrodeposited Pl..
Electrochemical and biological performance of chronically stimulated conductive hydrogel electrodes
Ashley N Dalrymple, Ulises A Robles, Mario Huynh, Bryony A Nayagam, Rylie A Green, Laura A Poole-Warren, James B Fallon, Robert K Shepherd
OBJECTIVE: Evaluate electrochemical properties, biological response, and surface characterization of a conductive hydrogel (CH) co..
Electrochemical and mechanical performance of reduced graphene oxide, conductive hydrogel, and electrodeposited Pt-Ir coated electrodes: an active in vitro study
Ashley N Dalrymple, Mario Huynh, Ulises Aregueta Robles, Jason B Marroquin, Curtis D Lee, Artin Petrossians, John J Whalen, Dan Li, Helena C Parkington, John S Forsythe, Rylie A Green, Laura A Poole-Warren, Robert K Shepherd, James B Fallon
OBJECTIVE: To systematically compare the in vitro electrochemical and mechanical properties of several electrode coatings that hav..
Neurotrophin gene augmentation by electrotransfer to improve cochlear implant hearing outcomes
Jeremy L Pinyon, Georg von Jonquieres, Edward N Crawford, Mayryl Duxbury, Amr Al Abed, Nigel H Lovell, Matthias Klugmann, Andrew K Wise, James B Fallon, Robert K Shepherd, Catherine S Birman, Waikong Lai, David McAlpine, Catherine McMahon, Paul M Carter, Ya Lang Enke, James F Patrick, Anne GM Schilder, Corinne Marie, Daniel Scherman
This Review outlines the development of DNA-based therapeutics for treatment of hearing loss, and in particular, considers the pot..