Cell Facilitated Controlled Radical Polymerization
Grant number: DP170104321 | Funding period: 2017 - 2019
This project aims to develop a controlled polymerisation method by combining reversible addition fragmentation chain (RAFT) polymerisation technology and the redox processes within bacterial cells. This polymerisation method will copy biological information in the bacterial cell surface into a growing polymer structure. Variations in the monomer structures and functionality will be used to control the incorporation of cell surface chemistry into the new polymer structure. Such cell-enabled controlled polymerisation could advance polymer synthesis resulting in biologically instructed polymer-mimics and new antibacterial agents.
Related publications (3)
Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids.
Alicia Rasines Mazo, Stephanie Allison-Logan, Fatemeh Karimi, Nicholas Jun-An Chan, Wenlian Qiu, Wei Duan, Neil M O'Brien-Simpson, Greg G Qiao
Polypeptides have attracted considerable attention in recent decades due to their inherent biodegradability and tunable cytocompat..