Nutritional strategies to ameliorate heat stress in pigs

Abstract

Glioblastoma multiforme (GBM) is a brain cancer and one of the deadliest forms of human cancer known. Intensification of chemotherapy often results in permanent morbidity in children. This study aims to develop a new nanocarrier that overcomes the blood€brain barrier (BBB), and to minimise drug-resistance in GBM to improve therapeutic efficacy and to minimise side effect. The BBB-penetrating performance, drug delivery efficiency, efficacy, pharmacokinetics and safety of this nanocarrier will be evaluated systematically using in-vitro and in-vivo models.